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    ghdc GH3 domain containing [ Danio rerio (zebrafish) ]

    Gene ID: 497449, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ghdcprovided by ZNC
    Official Full Name
    GH3 domain containingprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-165
    See related
    AllianceGenome:ZFIN:ZDB-GENE-050208-165
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ghdcl; im:7144495; zgc:163113
    Summary
    Predicted to enable acid-amino acid ligase activity. Predicted to be active in cytoplasm. Is expressed in proliferative region. Orthologous to human GHDC (GH3 domain containing). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ghdc in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (13527686..13549509, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (13489121..13512100, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene drosha ribonuclease III Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 4b Neighboring gene signal transducer and activator of transcription 5b Neighboring gene 5-oxoprolinase, ATP-hydrolysing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of JAK-STAT pathway components: mechanisms and role in immune system development. Liongue C, et al. PLoS One, 2012. PMID 22412924, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acid-amino acid ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GH3 domain-containing protein
    Names
    GH3 domain containing like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089358.1 → NP_001082827.1  GH3 domain-containing protein

      See identical proteins and their annotated locations for NP_001082827.1

      Status: PROVISIONAL

      Source sequence(s)
      BC135104
      UniProtKB/TrEMBL
      A4IGH7
      Conserved Domains (2) summary
      cl21606
      Location:2 → 463
      PLN02247; indole-3-acetic acid-amido synthetase
      pfam03321
      Location:1 → 453
      GH3; GH3 auxin-responsive promoter

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      13527686..13549509 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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