U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    emc8 ER membrane protein complex subunit 8 [ Danio rerio (zebrafish) ]

    Gene ID: 406679, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    emc8provided by ZNC
    Official Full Name
    ER membrane protein complex subunit 8provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2692
    See related
    Ensembl:ENSDARG00000017093 AllianceGenome:ZFIN:ZDB-GENE-040426-2692
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    noc4; cox4nb; fb54g02; zgc:56331; wu:fb54g02
    Summary
    Predicted to be part of EMC complex. Is expressed in pigment cell. Orthologous to human EMC8 (ER membrane protein complex subunit 8). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See emc8 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (30500690..30504652, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (30522436..30526398, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene Gse1 coiled-coil protein b Neighboring gene uncharacterized LOC137488295 Neighboring gene GINS complex subunit 2 Neighboring gene dual specificity phosphatase 22a Neighboring gene cytochrome c oxidase subunit 4I1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF. Seberg HE, et al. PLoS Genet, 2017 Mar. PMID 28249010, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of EMC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of EMC complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ER membrane protein complex subunit 8
    Names
    cox4 neighbor
    neighbor of cox4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213370.1 → NP_998535.1  ER membrane protein complex subunit 8

      See identical proteins and their annotated locations for NP_998535.1

      Status: PROVISIONAL

      Source sequence(s)
      BC046080
      UniProtKB/TrEMBL
      A0A8M1PPT0, Q7ZUY2
      Related
      ENSDARP00000013605.4, ENSDART00000028033.6
      Conserved Domains (1) summary
      cd08060
      Location:5 → 191
      MPN_UPF0172; Mov34/MPN/PAD-1 family: UPF0172 family of unknown function includes neighbor of COX4 (Noc4p)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      30500690..30504652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools