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    syne2b spectrin repeat containing, nuclear envelope 2b [ Danio rerio (zebrafish) ]

    Gene ID: 559348, updated on 2-Nov-2024

    Summary

    Official Symbol
    syne2bprovided by ZNC
    Official Full Name
    spectrin repeat containing, nuclear envelope 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-071218-5
    See related
    AllianceGenome:ZFIN:ZDB-GENE-071218-5
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    id:ibd5137; wu:fc12c11; wu:fc31e06; wu:fc62a06; si:dkey-249p9.3; si:dkeyp-77c8.1; si:dkeyp-77c8.2; si:dkeyp-77c8.3; si:dkeyp-77c8.4; si:dkeyp-77c8.5
    Summary
    Predicted to enable actin binding activity. Acts upstream of or within actin filament organization and epiboly. Predicted to be located in cytoplasm; cytoskeleton; and nuclear outer membrane. Is expressed in several structures, including axis; neural keel; primary neurons; shield; and tail bud. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 5. Orthologous to human SYNE2 (spectrin repeat containing nuclear envelope protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See syne2b in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    130
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (37075317..37270241, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (36949427..37134867, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487339 Neighboring gene FERM domain containing 6 Neighboring gene estrogen receptor 2b Neighboring gene glycoprotein hormone subunit beta 5 Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 5b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within epiboly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nesprin-2; spectrin repeat containing, nuclear envelope 2b

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      37075317..37270241 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068213093.1XP_068069194.1  nesprin-2 isoform X9

    2. XM_068213088.1XP_068069189.1  nesprin-2 isoform X4

    3. XM_068213092.1XP_068069193.1  nesprin-2 isoform X8

    4. XM_068213091.1XP_068069192.1  nesprin-2 isoform X7

    5. XM_068213094.1XP_068069195.1  nesprin-2 isoform X10

    6. XM_068213090.1XP_068069191.1  nesprin-2 isoform X6

    7. XM_068213089.1XP_068069190.1  nesprin-2 isoform X5

    8. XM_068213087.1XP_068069188.1  nesprin-2 isoform X3

    9. XM_068213086.1XP_068069187.1  nesprin-2 isoform X2

    10. XM_068213085.1XP_068069186.1  nesprin-2 isoform X1