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    ppp1r14bb protein phosphatase 1, regulatory (inhibitor) subunit 14Bb [ Danio rerio (zebrafish) ]

    Gene ID: 100000577, updated on 2-Nov-2024

    Summary

    Official Symbol
    ppp1r14bbprovided by ZNC
    Official Full Name
    protein phosphatase 1, regulatory (inhibitor) subunit 14Bbprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-595
    See related
    Ensembl:ENSDARG00000030161 AllianceGenome:ZFIN:ZDB-GENE-030616-595
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    plcb3n; ppp1r14b; zgc:91822; wu:fa01d09; wu:fb59a08; wu:fc32d08; wu:fk27d06; si:zc194c5.1; si:zc188c22.2
    Summary
    Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in innate immune response. Predicted to act upstream of or within regulation of phosphorylation. Predicted to be located in cytoplasm. Is expressed in head mesenchyme; intermediate cell mass of mesoderm; pectoral fin musculature; solid lens vesicle; and somite. Orthologous to human PPP1R14B (protein phosphatase 1 regulatory inhibitor subunit 14B). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See ppp1r14bb in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (60359399..60396578)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (60054174..60091341)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 8 member 4b Neighboring gene uncharacterized LOC137496230 Neighboring gene phospholipase C, beta 3 (phosphatidylinositol-specific) Neighboring gene BRMS1 transcriptional repressor and anoikis regulator Neighboring gene uncharacterized LOC110439982 Neighboring gene pyruvate carboxylase b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC91822

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
    Names
    protein phosphatase 1, regulatory (inhibitor) subunit 14B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002692.1NP_001002692.1  protein phosphatase 1, regulatory (inhibitor) subunit 14Bb

      See identical proteins and their annotated locations for NP_001002692.1

      Status: PROVISIONAL

      Source sequence(s)
      BC076513
      UniProtKB/TrEMBL
      F6NHA1, Q7ZZ37
      Related
      ENSDARP00000039826.5, ENSDART00000039827.6
      Conserved Domains (1) summary
      pfam05361
      Location:17128
      PP1_inhibitor; PKC-activated protein phosphatase-1 inhibitor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      60359399..60396578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068222095.1XP_068078196.1  protein phosphatase 1, regulatory (inhibitor) subunit 14Bb isoform X1

      Related
      ENSDARP00000113436.1, ENSDART00000145201.3