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    caprin1b cell cycle associated protein 1b [ Danio rerio (zebrafish) ]

    Gene ID: 406341, updated on 2-Nov-2024

    Summary

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    Official Symbol
    caprin1bprovided by ZNC
    Official Full Name
    cell cycle associated protein 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2020
    See related
    Ensembl:ENSDARG00000054272 AllianceGenome:ZFIN:ZDB-GENE-040426-2020
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rng105; caprin1; fe25d09; gpiap1l; zgc:55902; wu:fa96f04; wu:fe25d09; wu:fj66h11; ik:tdsubc_2d9; xx:tdsubc_2d9
    Summary
    Predicted to enable RNA binding activity. Predicted to act upstream of or within cell differentiation and negative regulation of translation. Predicted to be active in cytoplasm. Orthologous to human CAPRIN1 (cell cycle associated protein 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See caprin1b in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (38247797..38270596, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (38266789..38290281, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene nucleobindin 2b Neighboring gene si:dkey-10o6.2 Neighboring gene N-acetyltransferase 10 Neighboring gene uncharacterized LOC137488324 Neighboring gene LIM domain only 2 (rhombotin-like 1)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RNA granule protein 140 (RNG140), a paralog of RNG105 localized to distinct RNA granules in neuronal dendrites in the adult vertebrate brain. Shiina N, et al. J Biol Chem, 2010 Jul 30. PMID 20516077, Free PMC Article
    2. Understanding the complexity of epimorphic regeneration in zebrafish caudal fin tissue: A transcriptomic and proteomic approach. Banu S, et al. Genomics, 2022 Mar. PMID 35134499
    3. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    caprin-1b
    Names
    RNA granule protein 105
    cell cycle associated protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213068.1 → NP_998233.1  caprin-1b

      See identical proteins and their annotated locations for NP_998233.1

      Status: PROVISIONAL

      Source sequence(s)
      BC047196
      UniProtKB/TrEMBL
      Q802U4
      Related
      ENSDARP00000089659.3, ENSDART00000098889.5
      Conserved Domains (2) summary
      TIGR04260
      Location:560 → 638
      Cyano_gly_rpt; rSAM-associated Gly-rich repeat protein
      pfam12287
      Location:366 → 679
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      38247797..38270596 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214751.1 → XP_068070852.1  caprin-1b isoform X3

    2. XM_021467626.2 → XP_021323301.1  caprin-1b isoform X1

      UniProtKB/TrEMBL
      A0A8M9PM15
      Conserved Domains (2) summary
      pfam12287
      Location:357 → 680
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      cl25732
      Location:24 → 158
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_021467627.2 → XP_021323302.1  caprin-1b isoform X2

      UniProtKB/TrEMBL
      A0A8M9P113
      Conserved Domains (2) summary
      pfam12287
      Location:358 → 680
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      cl25732
      Location:24 → 158
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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