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    mmgt1 membrane magnesium transporter 1 [ Danio rerio (zebrafish) ]

    Gene ID: 402891, updated on 2-Nov-2024

    Summary

    Official Symbol
    mmgt1provided by ZNC
    Official Full Name
    membrane magnesium transporter 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-65
    See related
    Ensembl:ENSDARG00000010553 AllianceGenome:ZFIN:ZDB-GENE-040801-65
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tmem32; zgc:92918
    Summary
    Predicted to enable magnesium ion transmembrane transporter activity. Predicted to contribute to membrane insertase activity. Predicted to be involved in magnesium ion transport; protein insertion into ER membrane by stop-transfer membrane-anchor sequence; and tail-anchored membrane protein insertion into ER membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of EMC complex. Predicted to be active in Golgi apparatus; early endosome; and plasma membrane. Orthologous to human MMGT1 (membrane magnesium transporter 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See mmgt1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (31615577..31618205, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (31275263..31277891, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene motile sperm domain containing 1 Neighboring gene integrator complex subunit 6 like Neighboring gene solute carrier family 9 member A6a Neighboring gene four and a half LIM domains 1a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables inorganic cation transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables magnesium ion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    contributes_to membrane insertase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in magnesium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein insertion into ER membrane by stop-transfer membrane-anchor sequence ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in tail-anchored membrane protein insertion into ER membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of EMC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of EMC complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in early endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in early endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ER membrane protein complex subunit 5
    Names
    transmembrane protein 32

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205599.1NP_991162.1  ER membrane protein complex subunit 5

      See identical proteins and their annotated locations for NP_991162.1

      Status: PROVISIONAL

      Source sequence(s)
      AY394962
      UniProtKB/Swiss-Prot
      Q6TLE4
      Related
      ENSDARP00000005525.6, ENSDART00000016592.8
      Conserved Domains (1) summary
      pfam10270
      Location:2661
      MMgT; Membrane magnesium transporter

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      31615577..31618205 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394915.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      171844..174442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)