hdlbpa high density lipoprotein binding protein a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hdlbpaprovided by ZNC
Official Full Name: high density lipoprotein binding protein aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2032
See related: Ensembl:ENSDARG00000009830 AllianceGenome:ZFIN:ZDB-GENE-030131-2032
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: HBP; cb591; cb811; hdlbp; wu:fb36d01; wu:fb94h08; wu:fc23d06; wu:fc75h07
Summary: Predicted to enable mRNA binding activity. Acts upstream of or within cellular response to estrogen stimulus. Predicted to be part of polysome. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; immature eye; and pectoral fin. Orthologous to human HDLBP (high density lipoprotein binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (26874839..26895750, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (26884278..26905206, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

high expression in the liver and ovary suggests a role for this molecule in the cumulative efficiency of fish intake of food or lipid transfer
Title: Molecular cloning and functional analysis of zebrafish high-density lipoprotein-binding protein.

Submit: New GeneRIF Correction

General gene information

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Markers

fb94h08.x1 (e-PCR)
- UniSTS:191852

fb94h08.x1 (e-PCR)
- UniSTS:191853

fc23d06.x1 (e-PCR)
- UniSTS:203891

AI942799 (e-PCR)
- UniSTS:205959

fb36d01.x1 (e-PCR)
- UniSTS:203145

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to estrogen stimulus	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: high density lipoprotein binding protein a

Names: high density lipoprotein-binding protein (vigilin)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201474.1 → NP_958882.1 high density lipoprotein binding protein a

See identical proteins and their annotated locations for NP_958882.1

Status: PROVISIONAL

Source sequence(s)

BC051153

UniProtKB/TrEMBL

Q7ZU44

Conserved Domains (1) summary

cd02394
Location:586 → 647

vigilin_like_KH; K homology RNA-binding domain_vigilin_like. The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

26874839..26895750 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005165939.5 → XP_005165996.1 high density lipoprotein binding protein a isoform X1

See identical proteins and their annotated locations for XP_005165996.1

UniProtKB/TrEMBL

A0A8M2BDG6, F1R9Y8

Related

ENSDARP00000017412.8, ENSDART00000011863.10

Conserved Domains (1) summary

cd02394
Location:586 → 647

vigilin_like_KH; K homology RNA-binding domain_vigilin_like. The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has ...