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    wdr75 WD repeat domain 75 [ Danio rerio (zebrafish) ]

    Gene ID: 368478, updated on 17-Aug-2024

    Summary

    Official Symbol
    wdr75provided by ZNC
    Official Full Name
    WD repeat domain 75provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-5
    See related
    Ensembl:ENSDARG00000040730 AllianceGenome:ZFIN:ZDB-GENE-030616-5
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb990; flj12519; zgc:55748; wu:fb53f09; wu:fb96h05; si:dz73o4.1; SI:dZ46I22.2; si:by113d7.2; si:by68f21.1; si:by134g18.1; si:xx-113d7.2
    Summary
    Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleolus. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; nervous system; and segmental plate. Orthologous to human WDR75 (WD repeat domain 75). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See wdr75 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (41120158..41153882, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (41318371..41352095, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene zgc:136439 Neighboring gene asparagine synthetase domain containing 1 Neighboring gene solute carrier family 40 member 1 Neighboring gene signal transducer and activator of transcription 4 Neighboring gene signal transducer and activator of transcription 1b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    WD repeat-containing protein 75

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200090.1NP_956384.1  WD repeat-containing protein 75

      See identical proteins and their annotated locations for NP_956384.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045446
      UniProtKB/Swiss-Prot
      Q7ZVR1, Q7ZZ52, Q8AUI8, Q8AW19, Q8JFV9
      Related
      ENSDARP00000059666.5, ENSDART00000059667.7
      Conserved Domains (3) summary
      COG2319
      Location:23318
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:6199
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:25318
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      41120158..41153882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)