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    tmem50a transmembrane protein 50A [ Danio rerio (zebrafish) ]

    Gene ID: 406850, updated on 27-Mar-2024

    Summary

    Official Symbol
    tmem50aprovided by ZNC
    Official Full Name
    transmembrane protein 50Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2937
    See related
    Ensembl:ENSDARG00000015757 AllianceGenome:ZFIN:ZDB-GENE-040426-2937
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj33b04; zgc:55322; wu:fj33b04
    Summary
    Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to several human genes including TMEM50A (transmembrane protein 50A). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See tmem50a in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (45485185..45495565)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (45348281..45358661)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene arginine/serine-rich protein 1 Neighboring gene microsomal glutathione S-transferase 3b Neighboring gene Rh blood group, D antigen Neighboring gene macoilin 1b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in late endosome to vacuole transport via multivesicular body sorting pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213529.2NP_998694.1  transmembrane protein 50A

      See identical proteins and their annotated locations for NP_998694.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044368
      UniProtKB/TrEMBL
      B2GRI1, Q803R8
      Related
      ENSDARP00000009902.5, ENSDART00000019774.7
      Conserved Domains (1) summary
      pfam05255
      Location:8163
      UPF0220; uncharacterized protein family (UPF0220)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      45485185..45495565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157050.4XP_005157107.1  transmembrane protein 50A isoform X1

      See identical proteins and their annotated locations for XP_005157107.1

      UniProtKB/TrEMBL
      B2GRI1, Q803R8
      Related
      ENSDARP00000120219.1, ENSDART00000134730.3
      Conserved Domains (1) summary
      pfam05255
      Location:8163
      UPF0220; uncharacterized protein family (UPF0220)