isy1 ISY1 splicing factor homolog [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: isy1provided by ZNC
Official Full Name: ISY1 splicing factor homologprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5864
See related: Ensembl:ENSDARG00000063466 AllianceGenome:ZFIN:ZDB-GENE-030131-5864
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7159238; wu:fc23h01; wu:fi21h07; zgc:136785
Summary: Predicted to be involved in generation of catalytic spliceosome for second transesterification step and mRNA 3'-splice site recognition. Predicted to be located in nucleus. Predicted to be part of Prp19 complex and spliceosomal complex. Orthologous to several human genes including ISY1-RAB43 (ISY1-RAB43 readthrough). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (474433..486532, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (447941..459808, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc23h01.x1 (e-PCR)
- UniSTS:193168

fi21h07.x1 (e-PCR)
- UniSTS:197031

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in generation of catalytic spliceosome for second transesterification step	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within generation of catalytic spliceosome for second transesterification step	IEA Inferred from Electronic Annotation more info
involved_in mRNA 3'-splice site recognition	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of Prp19 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of post-mRNA release spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info
part_of post-spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: pre-mRNA-splicing factor ISY1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.