U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    dsk2 UBA domain protein Dph1/Dsk2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542667, updated on 22-Jun-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    dsk2
    Gene description
    UBA domain protein Dph1/Dsk2
    Locus tag
    SPOM_SPAC26A3.16
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    dph1; ucp5
    Old locus tag
    SPAC26A3.16
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See dsk2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3369727..3371384)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene mitofissin Atg44 Neighboring gene nucleoporin Nsp1 Neighboring gene ncRNA Neighboring gene N-methyltransferase Neighboring gene sorbose reductase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Myosin V spatially regulates microtubule dynamics and promotes the ubiquitin-dependent degradation of the fission yeast CLIP-170 homologue, Tip1. Martín-García R, et al. J Cell Sci, 2009 Nov 1. PMID 19808886
    2. Mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe. He X, et al. J Cell Sci, 1998 Jun. PMID 9601094
    3. The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain. Hänzelmann P, et al. J Biol Chem, 2010 Jun 25. PMID 20427284, Free PMC Article
    4. Involvement of rhp23, a Schizosaccharomyces pombe homolog of the human HHR23A and Saccharomyces cerevisiae RAD23 nucleotide excision repair genes, in cell cycle control and protein ubiquitination. Elder RT, et al. Nucleic Acids Res, 2002 Jan 15. PMID 11788722, Free PMC Article
    5. Dss1 is a 26S proteasome ubiquitin receptor. Paraskevopoulos K, et al. Mol Cell, 2014 Nov 6. PMID 25306921, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables polyubiquitin modification-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polyubiquitin modification-dependent protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ERAD pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    UBA domain protein Dph1/Dsk2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3369727..3371384
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019583.3 → NP_594159.1  UBA domain protein Dph1/Dsk2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594159.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10169
      Conserved Domains (4) summary
      smart00727
      Location:142 → 180
      STI1; Heat shock chaperonin-binding motif
      cd01809
      Location:4 → 75
      Scythe_N; Ubiquitin-like domain of Scythe protein
      smart00213
      Location:4 → 75
      UBQ; Ubiquitin homologues
      cd14324
      Location:310 → 351
      UBA_Dsk2p_like; UBA domain of Saccharomyces cerevisiae proteasome interacting protein Dsk2p and its homologs found in fungi
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous