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    chl1 ATP-dependent DNA helicase Chl1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543118, updated on 10-Jul-2024

    Summary

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    Gene symbol
    chl1
    Gene description
    ATP-dependent DNA helicase Chl1
    Locus tag
    SPOM_SPAC3G6.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPAC3G6.11
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    Genomic context

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    See chl1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (5398745..5402410)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GARP complex subunit Vps51 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein L41 Neighboring gene ncRNA Neighboring gene SNF2 family ATP-dependent chromatin remodeller Ino80

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe. Ansbach AB, et al. Mol Biol Cell, 2008 Feb. PMID 18045993, Free PMC Article
    2. Genetic controls of DNA damage avoidance in response to acetaldehyde in fission yeast. Noguchi C, et al. Cell Cycle, 2017 Jan 2. PMID 27687866, Free PMC Article
    3. Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4. Ranatunga NS, et al. G3 (Bethesda), 2016 Oct 13. PMID 27473316, Free PMC Article
    4. Essential domains of Schizosaccharomyces pombe Rad8 required for DNA damage response. Ding L, et al. G3 (Bethesda), 2014 May 28. PMID 24875629, Free PMC Article
    5. The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast. Mbogning J, et al. PLoS Genet, 2013. PMID 24385927, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA-templated DNA replication maintenance of fidelity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in establishment of sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in interstrand cross-link repair ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of chromatin IC
    Inferred by Curator
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in site of double-strand break IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-dependent DNA helicase Chl1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5398745..5402410
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020408.3 → NP_594977.1  ATP-dependent DNA helicase Chl1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594977.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14147
      Conserved Domains (3) summary
      smart00488
      Location:11 → 407
      DEXDc2; DEAD-like helicases superfamily
      TIGR00604
      Location:131 → 833
      rad3; DNA repair helicase (rad3)
      pfam13307
      Location:636 → 819
      Helicase_C_2; Helicase C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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