NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_021180.3Â RefSeqGene
- Range
-
6276..227907
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_1389
mRNA and Protein(s)
-
NM_001177984.3 → NP_001171455.1  sodium channel protein type 8 subunit alpha isoform 2
See identical proteins and their annotated locations for NP_001171455.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Isoforms 2 and 4 are the same length but differ in their sequence.
- Source sequence(s)
-
AB027567, AC013421, AC025097, AC068987, BX112779
- Consensus CDS
-
CCDS53794.1
- UniProtKB/Swiss-Prot
-
Q9UQD0
- Related
- ENSP00000440360.1, ENST00000545061.5
- Conserved Domains (6) summary
-
- smart00015
Location:1853 → 1874
- IQ; Calmodulin-binding motif
- cd13433
Location:1424 → 1476
- Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
- pfam00520
Location:1481 → 1735
- Ion_trans; Ion transport protein
- pfam06512
Location:991 → 1192
- Na_trans_assoc; Sodium ion transport-associated
- pfam11933
Location:502 → 688
- Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
- pfam16905
Location:1739 → 1802
- GPHH; Voltage-dependent L-type calcium channel, IQ-associated
-
NM_001330260.2 → NP_001317189.1  sodium channel protein type 8 subunit alpha isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains an alternate in-frame exon in the 5' coding region, compared to variant 1. Isoforms 1 and 3 are the same length but differ in their sequence.
- Source sequence(s)
-
AC013421, AC025097, AC068987, AC140060
- Consensus CDS
-
CCDS81692.1
- UniProtKB/Swiss-Prot
-
Q9UQD0
- UniProtKB/TrEMBL
-
Q6B4S4
- Related
- ENSP00000487583.2, ENST00000627620.5
- Conserved Domains (6) summary
-
- smart00015
Location:1894 → 1915
- IQ; Calmodulin-binding motif
- cd13433
Location:1465 → 1517
- Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
- pfam00520
Location:1197 → 1473
- Ion_trans; Ion transport protein
- pfam06512
Location:991 → 1192
- Na_trans_assoc; Sodium ion transport-associated
- pfam11933
Location:504 → 702
- Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
- pfam16905
Location:1788 → 1835
- GPHH; Voltage-dependent L-type calcium channel, IQ-associated
-
NM_001369788.1 → NP_001356717.1  sodium channel protein type 8 subunit alpha isoform 4
Status: REVIEWED
- Description
- Transcript Variant: Isoforms 2 and 4 are the same length but differ in their sequence.
- Source sequence(s)
-
AC013421, AC025097, AC068987, AC140060
- Consensus CDS
-
CCDS91697.1
- UniProtKB/TrEMBL
-
A0A590UK43
- Related
- ENSP00000499691.1, ENST00000668547.1
- Conserved Domains (6) summary
-
- smart00015
Location:1853 → 1874
- IQ; Calmodulin-binding motif
- cd13433
Location:1424 → 1476
- Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
- pfam00520
Location:1481 → 1735
- Ion_trans; Ion transport protein
- pfam06512
Location:991 → 1192
- Na_trans_assoc; Sodium ion transport-associated
- pfam11933
Location:502 → 692
- Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
- pfam16905
Location:1739 → 1802
- GPHH; Voltage-dependent L-type calcium channel, IQ-associated
-
NM_014191.4 → NP_055006.1  sodium channel protein type 8 subunit alpha isoform 1
See identical proteins and their annotated locations for NP_055006.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longest isoform (1). Isoforms 1 and 3 are the same length but differ in their sequence.
- Source sequence(s)
-
AB027567, AC013421, AC025097, AC068987
- Consensus CDS
-
CCDS44891.1
- UniProtKB/Swiss-Prot
- B9VWG8, O95788, Q9NYX2, Q9UPB2, Q9UQD0
- Related
- ENSP00000346534.4, ENST00000354534.11
- Conserved Domains (6) summary
-
- smart00015
Location:1894 → 1915
- IQ; Calmodulin-binding motif
- cd13433
Location:1465 → 1517
- Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
- pfam00520
Location:1197 → 1473
- Ion_trans; Ion transport protein
- pfam06512
Location:991 → 1192
- Na_trans_assoc; Sodium ion transport-associated
- pfam11933
Location:502 → 688
- Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
- pfam16905
Location:1780 → 1843
- GPHH; Voltage-dependent L-type calcium channel, IQ-associated
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000012.12Â Reference GRCh38.p14 Primary Assembly
- Range
-
51591233..51812864
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060936.1Â Alternate T2T-CHM13v2.0
- Range
-
51554795..51776384
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_175894.2: Suppressed sequence
- Description
- NM_175894.2: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.