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    si:dkey-22o12.2 si:dkey-22o12.2 [ Danio rerio (zebrafish) ]

    Gene ID: 100000151, updated on 28-Oct-2024

    Summary

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    Official Symbol
    si:dkey-22o12.2provided by ZNC
    Official Full Name
    si:dkey-22o12.2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-443
    See related
    Ensembl:ENSDARG00000091513 AllianceGenome:ZFIN:ZDB-GENE-060503-443
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    c3orf70a; si:dkey-24b15.2
    Summary
    Involved in circadian behavior and nervous system development. Orthologous to human C3orf70 (chromosome 3 open reading frame 70). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    all
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    Genomic context

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    See si:dkey-22o12.2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (30343714..30366840, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (29539783..29562893, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene im:7148405 Neighboring gene VPS8 subunit of CORVET complex Neighboring gene microRNA 740 Neighboring gene uncharacterized LOC103908879 Neighboring gene uncharacterized LOC137495518

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. C3orf70 Is Involved in Neural and Neurobehavioral Development. Ashikawa Y, et al. Pharmaceuticals (Basel), 2019 Oct 16. PMID 31623237, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within circadian behavior IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in circadian behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nervous system development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UPF0524 protein C3orf70 homolog A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126467.1 → NP_001119939.1  UPF0524 protein C3orf70 homolog A

      See identical proteins and their annotated locations for NP_001119939.1

      Status: PROVISIONAL

      Source sequence(s)
      CR382370
      UniProtKB/Swiss-Prot
      Q1LY84
      Related
      ENSDARP00000105219.2, ENSDART00000125759.3
      Conserved Domains (1) summary
      pfam15823
      Location:8 → 269
      UPF0524; UPF0524 of C3orf70

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      30343714..30366840 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480583.2 → XP_021336258.1  UPF0524 protein C3orf70 homolog A isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q9Q3
      Conserved Domains (1) summary
      pfam15823
      Location:54 → 264
      UPF0524; UPF0524 of C3orf70

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394491.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      238279..261144 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395218.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      27348..50492 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1LY84.1 GenPept UniProtKB/Swiss-Prot:Q1LY84

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