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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011513.1Â RefSeqGene
- Range
-
117365..215232
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000927.5 → NP_000918.2  ATP-dependent translocase ABCB1 isoform 2
See identical proteins and their annotated locations for NP_000918.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 2, which is shorter than isoform 1. Variants 2, 3, and 4 all encode the same isoform (2).
- Source sequence(s)
-
AA776371, AC002457, AC005068, AK290159
- Consensus CDS
-
CCDS5608.1
- UniProtKB/Swiss-Prot
- A8K294, B5AK60, P08183, Q12755, Q14812
- UniProtKB/TrEMBL
- A1L471, A4D1D2
- Related
- ENSP00000265724.3, ENST00000265724.8
- Conserved Domains (1) summary
-
- PTZ00265
Location:53 → 1267
- PTZ00265; multidrug resistance protein (mdr1); Provisional
-
NM_001348944.2 → NP_001335873.1  ATP-dependent translocase ABCB1 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 2, which is shorter than isoform 1. Variants 2, 3, and 4 all encode the same isoform (2).
- Source sequence(s)
-
AC002457, AC005068
- Consensus CDS
-
CCDS5608.1
- UniProtKB/Swiss-Prot
- A8K294, B5AK60, P08183, Q12755, Q14812
- UniProtKB/TrEMBL
- A1L471, A4D1D2
- Conserved Domains (1) summary
-
- PTZ00265
Location:53 → 1267
- PTZ00265; multidrug resistance protein (mdr1); Provisional
-
NM_001348945.2 → NP_001335874.1  ATP-dependent translocase ABCB1 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AC002457, AC005068
- UniProtKB/TrEMBL
-
A1L471
- Conserved Domains (1) summary
-
- PTZ00265
Location:123 → 1337
- PTZ00265; multidrug resistance protein (mdr1); Provisional
-
NM_001348946.2 → NP_001335875.1  ATP-dependent translocase ABCB1 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (2) with a shorter N-terminus, compared to isoform 1. Variants 2, 3, and 4 all encode the same isoform (2).
- Source sequence(s)
-
AB208970, AC005068, AY425005, BC130424, EU852583
- Consensus CDS
-
CCDS5608.1
- UniProtKB/Swiss-Prot
- A8K294, B5AK60, P08183, Q12755, Q14812
- UniProtKB/TrEMBL
- A1L471, A4D1D2
- Related
- ENSP00000478255.1, ENST00000622132.5
- Conserved Domains (1) summary
-
- PTZ00265
Location:53 → 1267
- PTZ00265; multidrug resistance protein (mdr1); Provisional
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14Â Reference GRCh38.p14 Primary Assembly
- Range
-
87503017..87713295 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1Â Alternate T2T-CHM13v2.0
- Range
-
88752787..88963178 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)