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    PF3D7_1463700 cyclin 1 [ Plasmodium falciparum 3D7 ]

    Gene ID: 812187, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1463700
    Gene description
    cyclin 1
    Locus tag
    PF3D7_1463700
    See related
    PlasmoDB:PF3D7_1463700; VEuPathDB:PF3D7_1463700
    Gene type
    protein coding
    RNA name
    cyclin 1
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1463700 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    1
    Sequence:
    Chromosome: 14; NC_037283.1 (2581543..2582523)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene fam-a protein Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene mitochondrial ribosomal protein S6-2 precursor, putative Neighboring gene EF-hand calcium-binding domain-containing protein, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Malaria Parasite Cyclin H Homolog PfCyc1 Is Required for Efficient Cytokinesis in Blood-Stage Plasmodium falciparum. Robbins JA, et al. mBio, 2017 Jun 13. PMID 28611247, Free PMC Article
    2. Activation of a Plasmodium falciparum cdc2-related kinase by heterologous p25 and cyclin H. Functional characterization of a P. falciparum cyclin homologue. Le Roch K, et al. J Biol Chem, 2000 Mar 24. PMID 10722743
    3. The malarial CDK Pfmrk and its effector PfMAT1 phosphorylate DNA replication proteins and co-localize in the nucleus. Jirage D, et al. Mol Biochem Parasitol, 2010 Jul. PMID 20332005
    4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of cyclin-dependent protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cell cycle process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      2581543..2582523
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348743.1 → XP_001348779.1  cyclin 1 [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348779.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024UZW8, A0A024WZE7, A0A2I0C1J0, Q8IKK0, Q9NG01, W4IWC5, W7FDS4, W7FHY9, W7J4Y6
      Conserved Domains (1) summary
      cd20524
      Location:5 → 147
      CYCLIN_CCNH_rpt1; first cyclin box found in cyclin-H (CCNH) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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