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    PF3D7_0826700 receptor for activated c kinase [ Plasmodium falciparum 3D7 ]

    Gene ID: 2655468, updated on 17-May-2024

    Summary

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    Gene symbol
    PF3D7_0826700
    Gene description
    receptor for activated c kinase
    Primary source
    PlasmoDB:PF3D7_0826700
    Locus tag
    PF3D7_0826700
    See related
    VEuPathDB:PF3D7_0826700
    Gene type
    protein coding
    RNA name
    receptor for activated c kinase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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    Genomic context

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    See PF3D7_0826700 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    2
    Sequence:
    Chromosome: 8; NC_004329.3 (1160164..1161708, complement)

    Chromosome 8 - NC_004329.3Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugation factor E4 B, putative Neighboring gene SNARE protein, putative Neighboring gene ncRNA Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene ATP-dependent RNA helicase DBP10, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_004329.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Receptor for Activated C-Kinase 1 (PfRACK1) is required for Plasmodium falciparum intra-erythrocytic proliferation. Blomqvist K, et al. Mol Biochem Parasitol, 2017 Jan. PMID 27732881, Free PMC Article
    2. The plasmodium receptor for activated C kinase protein inhibits Ca(2+) signaling in mammalian cells. Sartorello R, et al. Biochem Biophys Res Commun, 2009 Nov 27. PMID 19748487, Free PMC Article
    3. Human malaria parasites display a receptor for activated C kinase ortholog. Madeira L, et al. Biochem Biophys Res Commun, 2003 Jul 11. PMID 12821141
    4. 20S proteasomes secreted by the malaria parasite promote its growth. Dekel E, et al. Nat Commun, 2021 Feb 19. PMID 33608523, Free PMC Article
    5. Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome. Abdi A, et al. Wellcome Open Res, 2017. PMID 28944300, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of cell division IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular vesicle HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    receptor for activated c kinase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004329.3 Reference assembly

      Range
      1160164..1161708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001349222.1 → XP_001349258.1  receptor for activated c kinase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001349258.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024V731, A0A024VRY7, A0A024W8W2, A0A024WT44, A0A024XA36, A0A0L7KCD3, Q7YST8, Q8IBA0, W4II79, W4ISR6, W7FEP3, W7G7W8, W7JPQ3, W7K711
      Conserved Domains (2) summary
      cd00200
      Location:19 → 317
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:24 → 70
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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