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    zw10 zw10 kinetochore protein [ Danio rerio (zebrafish) ]

    Gene ID: 393110, updated on 21-Sep-2024

    Summary

    Official Symbol
    zw10provided by ZNC
    Official Full Name
    zw10 kinetochore proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-800
    See related
    Ensembl:ENSDARG00000018738 AllianceGenome:ZFIN:ZDB-GENE-040426-800
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55782
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and mitotic spindle assembly checkpoint signaling. Predicted to act upstream of or within cell division and mitotic cell cycle. Predicted to be located in cytoplasm; kinetochore; and nucleus. Predicted to be part of RZZ complex. Orthologous to human ZW10 (zw10 kinetochore protein). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See zw10 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (23036294..23046562, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (22999689..23009957, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene retinoblastoma 1 Neighboring gene lysophosphatidic acid receptor 6-like Neighboring gene dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) Neighboring gene ubiquitin specific peptidase 28 Neighboring gene uncharacterized LOC137488814 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 3A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC55782

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic spindle assembly checkpoint signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of RZZ complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    centromere/kinetochore protein zw10 homolog
    Names
    ZW10 homolog, centromere/kinetochore protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200141.2NP_956435.1  centromere/kinetochore protein zw10 homolog

      See identical proteins and their annotated locations for NP_956435.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044489
      UniProtKB/TrEMBL
      Q803G9
      Related
      ENSDARP00000020574.7, ENSDART00000016167.8
      Conserved Domains (1) summary
      pfam06248
      Location:9611
      Zw10; Centromere/kinetochore Zw10

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      23036294..23046562 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)