asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: asz1provided by ZNC
Official Full Name: ankyrin repeat, SAM and basic leucine zipper domain containing 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-988
See related: Ensembl:ENSDARG00000004823 AllianceGenome:ZFIN:ZDB-GENE-040426-988
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: gasz; zgc:56332
Summary: Predicted to be involved in piRNA metabolic process. Predicted to act upstream of or within several processes, including gene silencing by RNA; meiotic cell cycle; and spermatogenesis. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Predicted to be active in pi-body. Is expressed in oocyte stage I. Orthologous to human ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (20642381..20674121, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (20653315..20685055, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

sequence and molecular evolution
Title: Identification and characterization of evolutionarily conserved pufferfish, zebrafish, and frog orthologs of GASZ.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within meiotic cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within spermatogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in pi-body	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200230.1 → NP_956524.1 ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

See identical proteins and their annotated locations for NP_956524.1

Status: PROVISIONAL

Source sequence(s)

BC046081

UniProtKB/TrEMBL

Q7ZUY1

Related

ENSDARP00000021759.5, ENSDART00000005145.6

Conserved Domains (6) summary

cd09521
Location:272 → 335

SAM_ASZ1; SAM domain of ASZ1 subfamily

smart00454
Location:276 → 335

SAM; Sterile alpha motif

cd00204
Location:79 → 204

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:51 → 148

Ank_2; Ankyrin repeats (3 copies)

pfam13857
Location:136 → 191

Ank_5; Ankyrin repeats (many copies)

sd00045
Location:79 → 148

ANK; ANK repeat [structural motif]