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    fdx2 ferredoxin 2 [ Danio rerio (zebrafish) ]

    Gene ID: 767726, updated on 12-Sep-2024

    Summary

    Official Symbol
    fdx2provided by ZNC
    Official Full Name
    ferredoxin 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-1046
    See related
    Ensembl:ENSDARG00000052190 AllianceGenome:ZFIN:ZDB-GENE-060929-1046
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fdx1l; zgc:153554
    Summary
    Predicted to enable 2 iron, 2 sulfur cluster binding activity; electron transfer activity; and metal ion binding activity. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Orthologous to human FDX2 (ferredoxin 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See fdx2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (149405..152955)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (131354..134904)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene kelch-like ECH-associated protein 1b Neighboring gene sphingosine-1-phosphate receptor 5b Neighboring gene zinc finger GATA like protein 1 Neighboring gene uncharacterized LOC137495904 Neighboring gene LYL1 basic helix-loop-helix family member

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC153554

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables electron transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables electron transfer activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within P450-containing electron transport chain IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in [2Fe-2S] cluster assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of [4Fe-4S] cluster assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in electron transport chain IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ferredoxin-2, mitochondrial
    Names
    adrenodoxin-like protein, mitochondrial
    ferredoxin 1-like
    ferredoxin-1-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076664.2NP_001070132.1  ferredoxin-2, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001070132.1

      Status: VALIDATED

      Source sequence(s)
      CABZ01066699, EH493611, EH559468, EH612574
      UniProtKB/Swiss-Prot
      Q08C57
      Related
      ENSDARP00000131094.2, ENSDART00000161154.2
      Conserved Domains (1) summary
      PLN02593
      Location:80195
      PLN02593; adrenodoxin-like ferredoxin protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      149405..152955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)