U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    MPL MPL proto-oncogene, thrombopoietin receptor [ Numida meleagris (helmeted guineafowl) ]

    Gene ID: 110402572, updated on 15-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    MPL
    Gene description
    MPL proto-oncogene, thrombopoietin receptor
    See related
    Ensembl:ENSNMEG00000021266
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Numida meleagris
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MPL in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    100 current NumMel1.0 (GCF_002078875.1) 7 NC_034415.1 (19611451..19616222)

    Chromosome 7 - NC_034415.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 125 Neighboring gene chromosome 7 C1orf210 homolog Neighboring gene tyrosine kinase with immunoglobulin like and EGF like domains 1 Neighboring gene cell division cycle 20 Neighboring gene ELOVL fatty acid elongase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_034415.1 Chromosome 7 Reference NumMel1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hemopoiesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    thrombopoietin receptor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NumMel1.0 Primary Assembly

    Genomic

    1. NC_034415.1 Reference NumMel1.0 Primary Assembly

      Range
      19611451..19616222
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021404829.1 → XP_021260504.1  thrombopoietin receptor isoform X1

      Conserved Domains (3) summary
      cd00063
      Location:142 → 267
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:37 → 135
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      pfam00041
      Location:377 → 481
      fn3; Fibronectin type III domain

    2. XM_021404830.1 → XP_021260505.1  thrombopoietin receptor isoform X2

      Conserved Domains (3) summary
      cd00063
      Location:142 → 267
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:37 → 135
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      pfam00041
      Location:377 → 481
      fn3; Fibronectin type III domain

    3. XM_021404833.1 → XP_021260508.1  thrombopoietin receptor isoform X5

      Conserved Domains (3) summary
      cd00063
      Location:142 → 267
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:37 → 135
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      pfam00041
      Location:377 → 481
      fn3; Fibronectin type III domain

    4. XM_021404834.1 → XP_021260509.1  thrombopoietin receptor isoform X6

      Conserved Domains (3) summary
      cd00063
      Location:142 → 267
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:37 → 135
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      pfam00041
      Location:377 → 481
      fn3; Fibronectin type III domain

    5. XM_021404832.1 → XP_021260507.1  thrombopoietin receptor isoform X4

      Conserved Domains (3) summary
      cd00063
      Location:142 → 267
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:37 → 135
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      pfam00041
      Location:377 → 459
      fn3; Fibronectin type III domain

    6. XM_021404835.1 → XP_021260510.1  thrombopoietin receptor isoform X7

      Conserved Domains (3) summary
      cd00063
      Location:142 → 267
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:37 → 135
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      pfam00041
      Location:377 → 456
      fn3; Fibronectin type III domain

    7. XM_021404836.1 → XP_021260511.1  thrombopoietin receptor isoform X8

      Conserved Domains (3) summary
      cd00063
      Location:142 → 267
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:37 → 135
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      cl21522
      Location:377 → 447
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    8. XM_021404831.1 → XP_021260506.1  thrombopoietin receptor isoform X3

      Conserved Domains (3) summary
      cd00063
      Location:140 → 265
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:33 → 133
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      pfam00041
      Location:375 → 479
      fn3; Fibronectin type III domain

    9. XM_021404837.1 → XP_021260512.1  thrombopoietin receptor isoform X9

      Related
      ENSNMET00000036494.1
      Conserved Domains (3) summary
      cd00063
      Location:140 → 265
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:33 → 133
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
      pfam00041
      Location:375 → 457
      fn3; Fibronectin type III domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.