ablim3 actin binding LIM protein family, member 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ablim3provided by ZNC
Official Full Name: actin binding LIM protein family, member 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-070112-1122
See related: Ensembl:ENSDARG00000088168 AllianceGenome:ZFIN:ZDB-GENE-070112-1122
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb51g06; im:7152284; wu:fb51g06; zgc:158673; zgc:198293; si:dkey-23o10.3
Summary: Predicted to enable actin filament binding activity. Predicted to be involved in cilium assembly and lamellipodium assembly. Predicted to act upstream of or within actin cytoskeleton organization and transcription, DNA-templated. Predicted to be located in cytoplasm. Predicted to be active in stress fiber. Is expressed in notochord and somite. Orthologous to human ABLIM3 (actin binding LIM protein family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (34634140..34771916, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (34295075..34431624, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cytoskeleton organization	IEA Inferred from Electronic Annotation more info
involved_in lamellipodium assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in actin cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in stress fiber	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: actin-binding LIM protein 3

Names: actin-binding LIM protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080598.1 → NP_001074067.1 actin-binding LIM protein 3

See identical proteins and their annotated locations for NP_001074067.1

Status: PROVISIONAL

Source sequence(s)

BC129372

UniProtKB/TrEMBL

A0A8N7UYL2, A1L269, F1R1G1

Related

ENSDARP00000116596.2, ENSDART00000141157.5

Conserved Domains (6) summary

smart00153
Location:648 → 683

VHP; Villin headpiece domain

cd09327
Location:23 → 74

LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins

cd09328
Location:79 → 134

LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins

cd09329
Location:152 → 203

LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins

cd09330
Location:211 → 266

LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins

pfam16182
Location:294 → 647

AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007125.7 Reference GRCz11 Primary Assembly

Range

34634140..34771916 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005173321.5 → XP_005173378.1 actin-binding LIM protein 3 isoform X1

UniProtKB/TrEMBL

A0A0R4IXJ5, A0A8M2BL22

Related

ENSDARP00000140642.2, ENSDART00000160598.2

Conserved Domains (6) summary

smart00153
Location:649 → 684

VHP; Villin headpiece domain

cd09327
Location:24 → 75

LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins

cd09328
Location:80 → 135

LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins

cd09329
Location:153 → 204

LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins

cd09330
Location:212 → 267

LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins

pfam16182
Location:295 → 648

AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM