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    galntl6 polypeptide N-acetylgalactosaminyltransferase like 6 [ Danio rerio (zebrafish) ]

    Gene ID: 568915, updated on 12-Sep-2024

    Summary

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    Official Symbol
    galntl6provided by ZNC
    Official Full Name
    polypeptide N-acetylgalactosaminyltransferase like 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090312-115
    See related
    Ensembl:ENSDARG00000040048 AllianceGenome:ZFIN:ZDB-GENE-090312-115
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-15e22.3
    Summary
    Predicted to enable carbohydrate binding activity and hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Orthologous to human GALNTL6 (polypeptide N-acetylgalactosaminyltransferase like 6). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See galntl6 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (37752392..38131815)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (37033096..37412641)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene si:dkeyp-13d11.1 Neighboring gene si:dkeyp-13d11.2 Neighboring gene uncharacterized LOC137495611 Neighboring gene uncharacterized LOC101883643 Neighboring gene uncharacterized LOC137495280 Neighboring gene UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7 Neighboring gene high mobility group box 2a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants. Ma Z, et al. Sci Rep, 2017 Sep 4. PMID 28871129, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    polypeptide N-acetylgalactosaminyltransferase-like 6
    NP_001139074.1
    XP_005160048.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145602.1 → NP_001139074.1  polypeptide N-acetylgalactosaminyltransferase-like 6

      See identical proteins and their annotated locations for NP_001139074.1

      Status: PROVISIONAL

      Source sequence(s)
      BX927375, CR391923, CT583668, CU462871
      UniProtKB/TrEMBL
      A0A8M1NTE2, B8A6C4
      Related
      ENSDARP00000150300.1, ENSDART00000189756.1
      Conserved Domains (4) summary
      cd02510
      Location:142 → 437
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      cd00161
      Location:455 → 583
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:453 → 581
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
      pfam10111
      Location:142 → 404
      Glyco_tranf_2_2; Glycosyltransferase like family 2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      37752392..38131815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159991.5 → XP_005160048.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X1

      See identical proteins and their annotated locations for XP_005160048.1

      UniProtKB/TrEMBL
      A0A8M1NTE2, B8A6C4
      Related
      ENSDARP00000119502.1, ENSDART00000139448.3
      Conserved Domains (4) summary
      cd02510
      Location:142 → 437
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      cd00161
      Location:455 → 583
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:453 → 581
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
      pfam10111
      Location:142 → 404
      Glyco_tranf_2_2; Glycosyltransferase like family 2
    Nucleotide Protein
    Heading Accession and Version

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