Cnst consortin, connexin sorting protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Cnstprovided by RGD
Full Name: consortin, connexin sorting proteinprovided by RGD
Primary source: RGD:1564833
See related: EnsemblRapid:ENSRNOG00000002710 AllianceGenome:RGD:1564833
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564833
Summary: Predicted to enable connexin binding activity and phosphatase binding activity. Predicted to be involved in positive regulation of Golgi to plasma membrane protein transport. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane; trans-Golgi network; and transport vesicle. Orthologous to human CNST (consortin, connexin sorting protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Muscle (RPKM 196.4), Heart (RPKM 84.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q26

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (93828694..93905497)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (91296740..91373531)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (97838325..97915131)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables connexin binding	IBA Inferred from Biological aspect of Ancestor more info
enables connexin binding	ISO Inferred from Sequence Orthology more info
enables phosphatase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in positive regulation of Golgi to plasma membrane protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of Golgi to plasma membrane protein transport	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	IEA Inferred from Electronic Annotation more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
is_active_in trans-Golgi network	IBA Inferred from Biological aspect of Ancestor more info
located_in trans-Golgi network	ISO Inferred from Sequence Orthology more info
is_active_in transport vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in transport vesicle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: consortin; consortin, connexin sorting protein

Names: consortin-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001430792.1 → NP_001417721.1 consortin, connexin sorting protein isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000013
NM_001430793.1 → NP_001417722.1 consortin, connexin sorting protein isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000013

UniProtKB/TrEMBL

A6JGF5