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    uggt1 UDP-glucose glycoprotein glucosyltransferase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 553288, updated on 14-Nov-2024

    Summary

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    Official Symbol
    uggt1provided by ZNC
    Official Full Name
    UDP-glucose glycoprotein glucosyltransferase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061103-619
    See related
    Ensembl:ENSDARG00000054746 AllianceGenome:ZFIN:ZDB-GENE-061103-619
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:152896
    Summary
    Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Predicted to be involved in ERAD pathway and protein N-linked glycosylation via asparagine. Predicted to act upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Orthologous to human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See uggt1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (40830810..40890029, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (40976576..41035817, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488024 Neighboring gene uncharacterized LOC137487481 Neighboring gene heparan sulfate 6-O-sulfotransferase 1a Neighboring gene uncharacterized LOC137488025 Neighboring gene uncharacterized LOC110438100

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables UDP-glucose:glycoprotein glucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum lumen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glucose:glycoprotein glucosyltransferase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077534.1 → NP_001071002.1  UDP-glucose:glycoprotein glucosyltransferase 1 precursor

      See identical proteins and their annotated locations for NP_001071002.1

      Status: PROVISIONAL

      Source sequence(s)
      BC125832
      UniProtKB/TrEMBL
      A0JMD3
      Related
      ENSDARP00000148534.1, ENSDART00000191746.1
      Conserved Domains (2) summary
      cd06432
      Location:1226 → 1473
      GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family
      pfam06427
      Location:22 → 1171
      UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      40830810..40890029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480334.2 → XP_021336009.2  UDP-glucose:glycoprotein glucosyltransferase 1 isoform X1

      Related
      ENSDARP00000107250.3, ENSDART00000123886.3
    Nucleotide Protein Strain
    Heading Accession and Version

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