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    acot20 acyl-CoA thioesterase 20 [ Danio rerio (zebrafish) ]

    Gene ID: 553440, updated on 2-Nov-2024

    Summary

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    Official Symbol
    acot20provided by ZNC
    Official Full Name
    acyl-CoA thioesterase 20provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041001-182
    See related
    Ensembl:ENSDARG00000042510 AllianceGenome:ZFIN:ZDB-GENE-041001-182
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-11e23.4
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Is expressed in liver. Orthologous to several human genes including ACOT1 (acyl-CoA thioesterase 1); ACOT2 (acyl-CoA thioesterase 2); and ACOT4 (acyl-CoA thioesterase 4). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See acot20 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (28935409..28941112)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (29032515..29038233)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene serine and arginine rich splicing factor 5b Neighboring gene sushi domain containing 6 Neighboring gene acyl-CoA thioesterase 21 Neighboring gene G protein-coupled receptor 176

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of male zebrafish livers chronically exposed to perfluorononanoic acid. Zhang W, et al. Environ Int, 2012 Jul. PMID 21481936
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables thiolester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within acyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    acyl-coenzyme A thioesterase 1; uncharacterized protein LOC553440
    Names
    CTE1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      28935409..28941112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_691619.7 → XP_696711.3  acyl-coenzyme A thioesterase 1

      UniProtKB/TrEMBL
      A0A8N7URB7, Q5SPG8
      Related
      ENSDARP00000062337.4, ENSDART00000062338.5
      Conserved Domains (2) summary
      pfam04775
      Location:40 → 154
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      pfam08840
      Location:221 → 430
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal
    Nucleotide Protein Strain
    Heading Accession and Version

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