| CDCA5 accelerates progression of breast cancer by promoting the binding of E2F1 and FOXM1. | CDCA5 accelerates progression of breast cancer by promoting the binding of E2F1 and FOXM1.
Xiong Y, Shi L, Li L, Yang W, Zhang H, Zhao X, Shen N., Free PMC Article | 07/26/2024 |
| CDCA5 promoted cell invasion and migration by activating TGF-beta1 pathway in human ovarian cancer cells. | CDCA5 promoted cell invasion and migration by activating TGF-β1 pathway in human ovarian cancer cells.
Zhang Q, Zhang R, Li Y, Yang X., Free PMC Article | 04/1/2024 |
| KLF5-mediated CDCA5 expression promotes tumor development and progression of epithelial ovarian carcinoma. | KLF5-mediated CDCA5 expression promotes tumor development and progression of epithelial ovarian carcinoma.
Chen X, Zhou M, Ma S, Wu H, Cai H. | 06/16/2023 |
| CDCA5 promotes the progression of breast cancer and serves as a potential prognostic biomarker. | CDCA5 promotes the progression of breast cancer and serves as a potential prognostic biomarker.
Hu H, Xiang Y, Zhang XY, Deng Y, Wan FJ, Huang Y, Liao XH, Zhang TC., Free PMC Article | 09/3/2022 |
| Loss of cell division cycleassociated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinoma. | Loss of cell division cycle‑associated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinoma.
Huang X, Huang Y, Lv Z, Wang T, Feng H, Wang H, Du S, Wu S, Shen D, Wang C, Li H, Wang B, Ma X, Zhang X., Free PMC Article | 06/11/2022 |
| Knockdown of CDCA5 suppresses malignant progression of breast cancer cells by regulating PDS5A. | Knockdown of CDCA5 suppresses malignant progression of breast cancer cells by regulating PDS5A.
Wang Y, Yao J, Zhu Y, Zhao X, Lv J, Sun F., Free PMC Article | 05/21/2022 |
| Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non-small cell lung cancer cells via p53-p21 signaling pathway. | Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non-small cell lung cancer cells via p53-p21 signaling pathway.
Shen W, Tong D, Chen J, Li H, Hu Z, Xu S, He S, Ge Z, Zhang J, Mao Q, Chen H, Xu G., Free PMC Article | 05/21/2022 |
| TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5. | TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5.
Jin X, Wang D, Lei M, Guo Y, Cui Y, Chen F, Sun W, Chen X., Free PMC Article | 05/14/2022 |
| CDCA5 is negatively regulated by miR-326 and boosts ovarian cancer progression. | CDCA5 is negatively regulated by miR-326 and boosts ovarian cancer progression.
Gao A, Hu Y, Zhu W. | 12/18/2021 |
| LINC01515 promotes nasopharyngeal carcinoma progression by serving as a sponge for miR-325 to up-regulate CDCA5. | LINC01515 promotes nasopharyngeal carcinoma progression by serving as a sponge for miR-325 to up-regulate CDCA5.
Liu D, Gong H, Tao Z, Chen S, Kong Y, Xiao B. | 11/27/2021 |
| Downregulation of CDCA5 Can Inhibit Cell Proliferation, Migration, and Invasion, and Induce Apoptosis of Prostate Cancer Cells. | Downregulation of CDCA5 Can Inhibit Cell Proliferation, Migration, and Invasion, and Induce Apoptosis of Prostate Cancer Cells.
Chong Y, Xue L. | 11/13/2021 |
| CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathway. | CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathway.
Ji J, Shen T, Li Y, Liu Y, Shang Z, Niu Y., Free PMC Article | 10/23/2021 |
| Cyclin-Dependent Kinase 1 (CDK1) is Co-Expressed with CDCA5: Their Functions in Gastric Cancer Cell Line MGC-803. | Cyclin-Dependent Kinase 1 (CDK1) is Co-Expressed with CDCA5: Their Functions in Gastric Cancer Cell Line MGC-803.
Huang Z, Zhang S, Du J, Zhang X, Zhang W, Huang Z, Ouyang P., Free PMC Article | 05/22/2021 |
| Higher expression of cell division cycle-associated protein 5 predicts poorer survival outcomes in hepatocellular carcinoma. | Higher expression of cell division cycle-associated protein 5 predicts poorer survival outcomes in hepatocellular carcinoma.
Hou S, Chen X, Li M, Huang X, Liao H, Tian B., Free PMC Article | 03/27/2021 |
| LMTK2 binds to KLC1 to direct axonal transport of p35 and its loss may contribute to Alzheimer's disease. | LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains.
Mórotz GM, Glennon EB, Gomez-Suaga P, Lau DHW, Robinson ED, Sedlák É, Vagnoni A, Noble W, Miller CCJ., Free PMC Article | 04/25/2020 |
| Rec8-Stag3 cohesin is shown to be susceptible to Wapl-dependent ring opening and sororin-mediated protection. | Studying meiotic cohesin in somatic cells reveals that Rec8-containing cohesin requires Stag3 to function and is regulated by Wapl and sororin.
Wolf PG, Cuba Ramos A, Kenzel J, Neumann B, Stemmann O. | 12/7/2019 |
| We define a molecular pathway through which SLU7 keeps in check the generation of truncated forms of the splicing factor SRSF3 (SRp20) (SRSF3-TR). Behaving as dominant negative, or by gain-of-function, SRSF3-TR impair the correct splicing and expression of the splicing regulator SRSF1 (ASF/SF2) and the crucial SCC protein sororin. | Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins.
Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa MU, Uriarte I, Arechederra M, Alignani D, Bárcena-Varela M, Álvarez-Sola G, Colyn L, Santamaría E, Sangro B, Rodriguez-Ortigosa C, Fernández-Barrena MG, Ávila MA, Berasain C., Free PMC Article | 10/12/2019 |
| These findings suggest that CDCA5 expression is associated with poor prognosis in patients with hepatocellular carcinoma. | CDCA5 overexpression is an Indicator of poor prognosis in patients with hepatocellular carcinoma (HCC).
Tian Y, Wu J, Chagas C, Du Y, Lyu H, He Y, Qi S, Peng Y, Hu J., Free PMC Article | 03/16/2019 |
| high CDCA5 expression was also an independent factor of disease-free survival for patients with acral melanoma | Gene expression screening identifies CDCA5 as a potential therapeutic target in acral melanoma.
Xu T, Ma M, Dai J, Yu S, Wu X, Tang H, Yu J, Yan J, Yu H, Chi Z, Si L, Sheng X, Cui C, Kong Y, Guo J. | 03/16/2019 |
| High CDCA5 expression is associated with hepatocellular carcinoma. | Silencing of CDCA5 inhibits cancer progression and serves as a prognostic biomarker for hepatocellular carcinoma.
Wang J, Xia C, Pu M, Dai B, Yang X, Shang R, Yang Z, Zhang R, Tao K, Dou K., Free PMC Article | 11/24/2018 |
| These results suggest that satellite I RNA plays a role in stabilizing RBMX and Sororin in the ncRNP complex to maintain proper sister chromatid cohesion. | RBMX is a component of the centromere noncoding RNP complex involved in cohesion regulation.
Cho Y, Ideue T, Nagayama M, Araki N, Tani T. | 09/29/2018 |
| Silencing of CDCA5 suppresses proliferation of gastric cancer cells by inducing G1-phase arrest via downregulating CCNE1. | Upregulation of CDCA5 promotes gastric cancer malignant progression via influencing cyclin E1.
Zhang Z, Shen M, Zhou G. | 02/17/2018 |
| Sororin participates in the regulation of centromeric cohesion during meiosis in collaboration with SGO2-PP2A. | Sororin loads to the synaptonemal complex central region independently of meiotic cohesin complexes.
Gómez R, Felipe-Medina N, Ruiz-Torres M, Berenguer I, Viera A, Pérez S, Barbero JL, Llano E, Fukuda T, Alsheimer M, Pendás AM, Losada A, Suja JA., Free PMC Article | 08/19/2017 |
| The results suggest that CDCA5 functions as a critical gene supporting oral squamous cell carcinoma progression and that targeting CDCA5 may be a useful therapeutic strategy for oral squamous cell carcinoma. | Therapeutic potential of targeting cell division cycle associated 5 for oral squamous cell carcinoma.
Tokuzen N, Nakashiro K, Tanaka H, Iwamoto K, Hamakawa H., Free PMC Article | 12/17/2016 |
| phosphorylation plays unexpected roles in regulating the subcellular localization of Sororin. | Multiple Levels of Regulation of Sororin by Cdk1 and Aurora B.
Borton MT, Rashid MS, Dreier MR, Taylor WR. | 11/5/2016 |