Identification of HTRA1, DPT and MXRA5 as potential biomarkers associated with osteoarthritis progression and immune infiltration.
Sun Y, Yang H, Guo J, Du J, Han S, Yang X., Free PMC Article

Rational correction of pathogenic conformational defects in HTRA1.
Beaufort N, Ingendahl L, Merdanovic M, Schmidt A, Podlesainski D, Richter T, Neumann T, Kuszner M, Vetter IR, Stege P, Burston SG, Filipovic A, Ruiz-Blanco YB, Bravo-Rodriguez K, Mieres-Perez J, Beuck C, Uebel S, Zobawa M, Schillinger J, Malik R, Todorov-Völgyi K, Rey J, Roberti A, Hagemeier B, Wefers B, Müller SA, Wurst W, Sanchez-Garcia E, Zimmermann A, Hu XY, Clausen T, Huber R, Lichtenthaler SF, Schmuck C, Giese M, Kaiser M, Ehrmann M, Dichgans M., Free PMC Article

Altered Elastin Turnover, Immune Response, and Age-Related Retinal Thinning in a Transgenic Mouse Model With RPE-Specific HTRA1 Overexpression.
Navneet S, Ishii M, Rohrer B., Free PMC Article

HTRA1-driven detachment of type I collagen from endoplasmic reticulum contributes to myocardial fibrosis in dilated cardiomyopathy.
Shi H, Yuan M, Cai J, Lan L, Wang Y, Wang W, Zhou J, Wang B, Yu W, Dong Z, Deng D, Qian Q, Li Y, Zhou X, Liu J., Free PMC Article

Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration.
Pan Y, Fu Y, Baird PN, Guymer RH, Das T, Iwata T.

HTRA1 promotes EMT through the HDAC6/Ac-α-tubulin pathway in human GBM cells.
Zhao W, Wu Y, Wang S, Zhao F, Liu W, Xue Z, Zhang L, Wang J, Han M, Li X, Huang B., Free PMC Article

Critical Dependence on Area in Relationship between ARMS2/HTRA1 Genotype and Faster Geographic Atrophy Enlargement: Age-Related Eye Disease Study 2 Report Number 33.
Agrón E, Domalpally A, Cukras CA, Chew EY, Keenan TDL, Age-Related Eye Disease Study 2 Research Group.,

Spontaneous malignant transformation of trigeminal schwannoma: consideration of responsible gene alterations for tumorigenesis-a case report.
Ogasawara N, Yamashita S, Yamasaki K, Kawano T, Kawano T, Muta J, Matsumoto F, Watanabe T, Ohta H, Yokogami K, Fukushima T, Sato Y, Takeshima H.

Inorganic arsenic exposure promotes malignant progression by HDAC6-mediated down-regulation of HTRA1.
Chen J, Lei C, Nie D, Ge H, Li J, Lei C, Wang W.

Upregulation of HTRA1 mediated by the lncRNA NEAT1/miR-141-3p axis contributes to endometriosis development through activating NLRP3 inflammasome-mediated pyroptotic cell death and cellular inflammation.
Li L, Ye K, Wang D.

Reticular Pseudodrusen Status, ARMS2/HTRA1 Genotype, and Geographic Atrophy Enlargement: Age-Related Eye Disease Study 2 Report 32.
Agrón E, Domalpally A, Cukras CA, Clemons TE, Chen Q, Swaroop A, Lu Z, Chew EY, Keenan TDL, AREDS and AREDS2 Research Groups., Free PMC Article

Disentangling the Impact of Reticular Pseudodrusen Phenotype and the ARMS2/HTRA1 Risk Allele in Geographic Atrophy: The AREDS 2 Study Report 32.
Huang BB, Fawzi AA.

Clinical features and pathogenicity assessment in patients with HTRA1-autosomal dominant disease.
He Z, Wang L, Zhang Y, Yin C, Niu Y.

High frequency of HTRA1 AND ABCC6 mutations in Japanese patients with adult-onset cerebral small vessel disease.
Uemura M, Hatano Y, Nozaki H, Ando S, Kondo H, Hanazono A, Iwanaga A, Murota H, Osakada Y, Osaki M, Kanazawa M, Kanai M, Shibata Y, Saika R, Miyatake T, Aizawa H, Ikeuchi T, Tomimoto H, Mizuta I, Mizuno T, Ishihara T, Onodera O., Free PMC Article

TGF-β/Smad Signalling Activation by HTRA1 Regulates the Function of Human Lens Epithelial Cells and Its Mechanism in Posterior Subcapsular Congenital Cataract.
Lin X, Yang T, Liu X, Fan F, Zhou X, Li H, Luo Y., Free PMC Article

Endoplasmic reticulum stress-regulated high temperature requirement A1 (HTRA1) modulates invasion and angiogenesis-related genes in human trophoblasts.
Yoshida K, Kusama K, Azumi M, Yoshie M, Kato K, Tamura K.

Novel mutations in HTRA1-related cerebral small vessel disease and comparison with CADASIL.
Zhang C, Zheng H, Li X, Li S, Li W, Wang Z, Niu S, Wang X, Zhang Z., Free PMC Article

Report of two pedigrees with heterozygous HTRA1 variants-related cerebral small vessel disease and literature review.
Zhou H, Jiao B, Ouyang Z, Wu Q, Shen L, Fang L., Free PMC Article

Polymorphism rs11200638 enhanced HtrA1 responsiveness and expression are associated with age-related macular degeneration.
He F, Li X, Cai S, Lu L, Zhang T, Yang M, Fan N, Wang X, Liu X., Free PMC Article

Forward and reverse degradomics defines the proteolytic landscape of human knee osteoarthritic cartilage and the role of the serine protease HtrA1.
Bhutada S, Li L, Willard B, Muschler G, Piuzzi N, Apte SS.

Hereditary cerebral small vessel disease: Assessment of a HTRA1 variant using protein stability predictors and 3D modelling.
Hidalgo Mayoral I, Martínez-Salio A, Llamas-Velasco S, Gómez-Majón I, Arteche-López A, Quesada-Espinosa JF, Palma Milla C, Lezana Rosales JM, Pérez de la Fuente R, Juárez Rufián A, Sierra Tomillo O, Sánchez Calvín MT, Gómez Rodríguez MJ, Ramos Gómez P, Villarejo-Galende A, Díaz-Guzmán J, Ortega-Casarrubios MÁ, Calleja-Castaño P, Moreno-García M.

The Phenotypic Course of Age-Related Macular Degeneration for ARMS2/HTRA1: The EYE-RISK Consortium.
Thee EF, Colijn JM, Cougnard-Grégoire A, Meester-Smoor MA, Verzijden T, Hoyng CB, Fauser S, Hense HW, Silva R, Creuzot-Garcher C, Ueffing M, Delcourt C, den Hollander AI, Klaver CCW, European Eye Epidemiology Consortium and EYE-RISK Project.

Melatonin regulates trophoblast pyroptosis, invasion and migration in preeclampsia by inhibiting HtrA1 transcription through the microRNA-520c-3p/SETD7 axis.
Liu Z, Chen B, Chang J, Feng L, Zhao X.

The multifaced role of HtrA1 in the development of joint and skeletal disorders.
Tossetta G, Fantone S, Licini C, Marzioni D, Mattioli-Belmonte M.

A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers' Serum on RPE Cells With AMD High-Risk Alleles.
Cai B, Zhang Z, Sun S, Lin T, Ke Y, Li Z, Yang J, Li X., Free PMC Article