Genome

Actinobacillus pleuropneumoniae Causes disease in pigs Lineage: Bacteria[37515]; Pseudomonadota[11108]; Gammaproteobacteria[4595]; Pasteurellales[139]; Pasteurellaceae[135]; Actinobacillus[18]; Actinobacillus pleuropneumoniae[1]

Actinobacillus pleuropneumoniae. This organism is an obligate parasite of pigs. The bacterium colonizes and invades the porcine lower respiratory tract and can survive phagocytosis by macrophages, eventually resulting in the death of the macrophage cell. Three RTS toxins, which result in cell damage, are produced by this organism.

Summary Sequence data:  genome assemblies: 85; sequence reads: 1  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 2.27554  median protein count: 2102  median GC%: 41.2 Publications (limited to 20 most recent records) Comparative genomics of 26 complete circular genomes of 18 different serotypes of Actinobacillus pleuropneumoniae. Donà V, et al. Microb Genom 2022 Feb O-Serogroups and Pathovirotypes of Escherichia coli Isolated from Post-Weaning Piglets Showing Diarrhoea and/or Oedema in South Korea. Byun JW, et al. Vet Sci 2021 Dec 21 Comparative Genomics of the First and Complete Genome of "Actinobacillus porcitonsillarum" Supports the Novel Species Hypothesis. Donà V, et al. Int J Genomics 2018 Complete Genome Sequence of MIDG2331, a Genetically Tractable Serovar 8 Clinical Isolate of Actinobacillus pleuropneumoniae. Bossé JT, et al. Genome Announc 2016 Jan 28 Draft Genome Sequences of Six Actinobacillus pleuropneumoniae Serotype 8 Brazilian Clinical Isolates: Insight into New Applications. Pereira MF, et al. Genome Announc 2015 Mar 5 Draft genome sequence of Actinobacillus pleuropneumoniae serotype 7 strain S-8. Li G, et al. J Bacteriol 2012 Dec Comparative genomic characterization of Actinobacillus pleuropneumoniae. Xu Z, et al. J Bacteriol 2010 Nov Draft genome sequences of Actinobacillus pleuropneumoniae serotypes 2 and 6. Zhan B, et al. J Bacteriol 2010 Nov The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b). Foote SJ, et al. J Bacteriol 2008 Feb Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of serotype 3 prevalent in China. Xu Z, et al. PLoS One 2008 Jan 16 Evaluation of an enzyme-linked immunosorbent assay for serological surveillance of infection with Actinobacillus pleuropneumoniae serotype 5 in pig herds. Klausen J, et al. Vet Microbiol 2002 Sep 2 Structure of the capsular polysaccharide of Actinobacillus pleuropneumoniae serotype 5b. Altman E, et al. Eur J Biochem 1992 Feb 15 Structural studies of the O-chains of the lipopolysaccharides produced by strains of Actinobacillus (Haemophilus) pleuropneumoniae serotype 5. Altman E, et al. Biochem Cell Biol 1990 Nov More...  Representative (genome information for reference and representative genomes) Reference genome:   Actinobacillus pleuropneumoniae 57675_E01 Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr 1 NZ_LR134515.1 LR134515.1 2.33 41.2 2,103 20 61 4 2,217 29 Dendrogram (based on genomic BLAST)