Expression data from non-infected and HAstV-1 infected Caco-2 cells

SLFN11 is widely expressed in pediatric sarcoma and induces variable sensitization to 1 replicative stress caused by DNA damaging agents

ADAR1 restricts ZBP1–mediated immune response and PANoptosis to promote tumorigenesis

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion

Integrated metabolomic and transcriptomic analysis reveals metabolic adaptation of rats to Abcg2/Abcb1a knockout

MyD88/IL-1R axis sustains immunosuppressive function of TAMs by regulating PD-1 expression in melanoma

The common germline TP53-R337H mutation is hypomorphic and confers incomplete tumor penetrance and late tumor onset in a mouse model

COVID-19 cytokines and the hyperactive immune response: Synergism of TNF-α and IFN-γ in triggering inflammation, tissue damage, and death

Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis

Homeostasis and transitional activation of regulatory T cells require c-Myc

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis

Effects of suberanilohydroxamic acid (SAHA) on HeLa cells

Transcription profiles of fate mapped IL17aiCre+flox/stop/flox-YFP+ TH17 cells, CD44intCD27+ TH17 cells and CD44hiCD27- TH17 cells from WT or Raptor-ko (flox/flox) mice after immunization with Myelin Oligodendrocyte Glycoprotein (MOG)

Hippo kinases Mst1 and Mst2 sense and amplify IL-2R−STAT5 signaling in Treg cells to establish stable regulatory activity

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

IRF8 regulates transcription of Naips for NLRC4 inflammasome activation

B cell development requires discrete regulation by PTEN-PI3K and mTOR pathways and the intricate interplay with IL-7 r-Stat5 signaling

IRF1 is a transcriptional regulator of ZBP1 promoting NLRP3 inflammasome activation and cell death during influenza virus infection

R-spondin 2 is required for optic vesicle morphogenesis and neuroretina specification in vivo and in vitro

Transcription profile of WT and LKB1 (encoded by the gene Stk11)-deficient Treg cells