Development of a ß-Globin Gene Replacement Strategy as a Therapeutic Approach for ß-Hemoglobinopathies

Manipulating the 3D organization of the largest synthetic yeast chromosome [WGS]

Manipulating the 3D organization of the largest synthetic yeast chromosome

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression [human sWGS]

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression [mouse sWGS]

Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity

Genomic and transcriptomic analysis of medulloblastoma

Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos

Divergent resistance mechanisms to HER2-targeted therapies in breast cancer

Whole-exome sequencing analysis of primary tumors and metastases from the NPK (Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+; R26R-CAG-LSL-EYFP/+) prostate cancer mouse model

Single Cell Transcriptional Analysis of Donor and Recipient Immune Cell Chimerism in the Rejecting Kidney Transplant

Complementation can maintain a quasispecies of drug sensitive and resistant HIV

Stimulation of oncogene-specific tumor infiltrating T-cells through combined vaccine and alpha-PD1 enable sustained anti-tumor responses against established HER2 breast cancer (BC)

Molecular basis of cisplatin resistance in testicular germ cell tumors

RNA-seq transcriptome profiling of hybrid (hawaii mother and bristol father) C. elegans H3K27me3 M+P+ vs. M+P- hermaphrodite germlines

Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex

Integrated genome and transcriptome sequencing from the same cell