Hyperglycemia-triggered lipid peroxidation destabilizes STAT4 and impairs anti-viral Th1 responses in type 2 diabetes

Comparative single-cell transcriptomics of human neuroblastoma and preclinical models reveal conservation of adrenergic cell state

Histone Methylation Patterns in Acute Leukemias are Defined by Genotype Independent of the Disease Phenotype

Identifying the molecular mechanisms that underlie impaired kidney development due to maternal diabetes.

RNA sequencing data of intestinal tissue from wild-type C57BL/6 mice and ITGB6-overexpressing transgenic mice

Enterococcus faecalis-derived lactate mediated suppression of NF-κB and ERK pathways in macrophages to promote polymicrobial wound infection

CRISPR-Cas9 Whole-Genome Screen Identify Critical Genes Regulating Cholesterol Metabolism in Macrophages

Retinoic acid induced meiosis initiation of female germline stem cells by remodeling three-dimensional chromatin structure [RNA-seq]

Rhizopus stolonifer displays necrotrophic behavior when infecting fruit in postharvest

Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior

Sodium myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis in pressure overloaded mouse hearts

Inhibition of RNA splicing triggers CHMP7 nuclear entry impacting TDP-43 function and leading to onset of ALS (RNA-Seq).

Two H3K23 histone methyltransferases, SET-32 and SET-21, function synergistically to promote germline nuclear RNAi, proper endogenous siRNA expression, and germline immortality in Caenorhabditis elegans [ChIP-seq]

Thyroid hormone receptor beta (THRβ1) is the major regulator of T3 action in human iPSC-derived hepatocytes

Effects of high doses of cholecacyferol on gene expression in the jejunum and colon of pigs

Type III interferons induce pyroptosis in gut epithelial cells and impair tissue repair upon intestinal injury.

Type III interferons induce pyroptosis in gut epithelial cells and impair tissue repair upon intestinal injury.

Tumor-intrinsic kinome landscape of pancreatic cancer reveals new therapeutic approaches

Local Delivery of an IL-15 Superagonist Using a Replicating Retrovirus Improves Survival and Lymphocyte Infiltration in Poorly Immunogenic Mouse Models of Glioblastoma

IL-18 engineered to avoid decoy-receptor binding enhances tumor rejection by anti-CTLA-4 in kidney cancer models through immune microenvironment remodeling.