Multiomic Analyses Reveal New Targets of Polycomb Repressor Complex 2 in Schwann Lineage Cells and Malignant Peripheral Nerve Sheath Tumors - ChIPseq

Redirecting the pioneering function of FOXA1 with covalent small molecules [ChIP-seq]

Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells

Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells [4C-seq]

Alveolar Soft Part Sarcoma is driven by ASPSCR1::TFE3-dependent and therapeutically targetable transcriptional programs [ATAC-Seq]

Reanalysis of TSA-Seq mapping to determine genomic coordinates for speckles-associated domains.

3D genome topology distinguishes molecular subgroups of medulloblastoma

Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response [ribosome profiling]

KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma

KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma [ChIP-seq]

Dynamic and distinct histone modifications facilitate human trophoblast lineage specification

Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer

Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer [ChIP-Seq]

Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms [ChIP-seq]

ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs

Alveolar Soft Part Sarcoma is driven by ASPSCR1::TFE3-dependent and therapeutically targetable transcriptional programs [ChIP-Seq]

Analysis of UV-induced DNA damage in human cells using CPD-seq 2.0

H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in paediatric high-grade glioma cells

CPSF6 regulates alternative polyadenylation and proliferation of cancer cell through phase separation

Phase Separation of FOXA1 Unpacks the Condensed Chromatin to Function as a Pioneer Factor