NR2E3 loss disrupts photoreceptor cell maturation and fate in human organoid models of retinal development

Automating iPSC generation to enable autologous photoreceptor cell replacement therapy

Chromatin accessibility and mitochondrial genotype from single cells of the retina and choroid in human MELAS (m.3243A>G) and control samples [scATAC-seq]

Gene expression from single cells of the retina and choroid in human MELAS (m.3243A>G) and control samples [scRNA-seq]

Multimodal sequencing (gene expression, chromatin accessibility, and mtDNA genotyping) of single cells of the RPE and choroid in human MELAS (m.3243A>G) and control samples

Multimodal single nuclei profiling of human macular and peripheral retinal pigment epithelial cells

Non-random distribution of mitochondrial m.3243A>G heteroplasmy in human retina and its impact on cellular phenotype