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Platform GPL104 Query DataSets for GPL104
Status Public on Apr 03, 2002
Title NIA Neuroarray
Technology type spotted DNA/cDNA
Distribution non-commercial
Organism Homo sapiens
 
Description The NIA Neuroarray is a focused 1152-clone cDNA microarray designed specifically for neuroscience applications.
Full details of clone preparation, printing, hybridization, image capture and spot quantification protocols used for this array can be found at the web link below.
The array template was last annotated March 2002.
Keywords = neuroarray, neuroscience
 
Web link http://www.grc.nia.nih.gov/branches/rrb/dna/neuroscience.pdf
Contributor(s) Barrett T, Vawter MP, Wood WH, Teichberg D, Donovan DM, Cheadle C, Becker KG
Citation(s) 11847435
Submission date Mar 15, 2002
Last update date Jun 22, 2020
Contact name Supriyo De
Organization name NIA-IRP, NIH
Department Laboratory of Genetics and Genomics
Lab Computational Biology & Genomics Core
Street address 251 Bayview Blvd
City Baltimore
State/province Maryland
ZIP/Postal code 21224
Country USA
 
Samples (6) GSM28446, GSM28534, GSM28535, GSM28536, GSM28537, GSM28538
Series (1)
GSE1656 GABAB-R evoked changes in mRNA transcription

Data table header descriptions
ID
GENE_NAME gene name
GENE_SYM gene symbol
GB_ACC GenBank accession number
UNIGENE
GENE Entrez GENE ID
CYTOBAND cytoband
EXP_AREA expression area
CLONE_ID IMAGE clone ID
SP_ID
SP_SUBCELL_LOC SwissProt subcellular location
SP_PROT_FAM_DESC SwissProt protein family description
SP_PROT_FUNC SwissProt protein function
PROTEIN_KEYWORDS SwissProt keywords
MEDLINE_ARTICLES Medline articles
PFAM_ID PFAM ID
PFAM_DESC PFAM description
KEGG_PATHWAY_NUM KEGG pathway number
GRID_POS microarray grid position
PIN_NO microarrayer pin number
PLATE clone plate number
ROW clone plate row
COLUMN clone plate column

Data table
ID GENE_NAME GENE_SYM GB_ACC UNIGENE GENE CYTOBAND EXP_AREA CLONE_ID SP_ID SP_SUBCELL_LOC SP_PROT_FAM_DESC SP_PROT_FUNC PROTEIN_KEYWORDS MEDLINE_ARTICLES PFAM_ID PFAM_DESC KEGG_PATHWAY_NUM GRID_POS PIN_NO PLATE ROW COLUMN
1 synaptosomal-associated protein, 23kD SNAP23 R98877 200863 GRID- 1-R1C1 2 2 a 12
2 neuritin R66101 103291 51299 6p25.1 infant brain;fetal heart;uterus (pregnant);heart;embryo;fetal lung;placenta;brain;fetal liver/spleen;endometrium (tumor);lung 140197 GRID- 1-R2C1 2 2 a 10
3 EphA1 EPHA1 N90246 89839 2041 7q32-q36 testis;parathyroid gland (tumor);liver;fetal liver/spleen;placenta 305606 Q15405 Type I membrane protein. Ephrin type-A receptor 1 precursor (EC 2.7.1.112) (Tyrosine-proteinkinase receptor EPH). RECEPTOR FOR MEMBERS OF THE EPHRIN-A FAMILY. BINDS WITH A LOW AFFINITY TO EPHRIN-A1. ATP-binding, Glycoprotein, Phosphorylation, Receptor, Repeat, Signal, Transferase, Transmembrane, Tyrosine-protein kinase 99299440 GRID- 1-R3C1 2 2 a 8
4 enolase 2, (gamma, neuronal) ENO2 AA450189 146580 2026 12p13 infant brain;retina;brain--cerebellum;fetal lung;fetal brain;brain;pineal gland;neuroepithelium (NT2RAMI);fibroblast;colon;NT2 neuronal precursor;multiple sclerosis lesions;lung (carcinoma);fetal heart;adrenal gland (tumor);ovary (tumor);HeLa (cell line);endometrium (tumor);melanocyte;T cells (Jurkat cell line);T cells (activated) 789147 00010, 00400 GRID- 1-R4C1 2 2 a 6
5 GTP cyclohydrolase 1 (dopa-responsive dystonia) GCH1 AA443688 86724 2643 14q22.1-q22.2 placenta;gall bladder;fetal liver/spleen;colon (carcinoma, cell line HCC);blood--white cells;T cells (activated);NT2 neuronal precursor;testis;lung (carcinoma);macrophage 783849 Q9Y4I8 GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I). ISOFORM GCH-1 IS THE FUNCTIONAL ENZYME, THE POTENTIAL FUNCTION OF THE ENZYMATICALLY INACTIVE ISOFORMS REMAINS UNKNOWN. Allosteric enzyme, Alternative splicing, Disease mutation, Hydrolase, Phenylketonuria, Phosphorylation, Polymorphism, Tetrahydrobiopterin biosynthesis 97252592 790 GRID- 1-R5C1 2 2 a 4
6 glial fibrillary acidic protein GFAP AA069414 1447 2670 17q21 brain;brain--cerebellum;infant brain;pineal gland;brain--hippocampus;multiple sclerosis lesions;retina;fetal brain;brain--frontal lobe;brain--right hemisphere 382693 GRID- 1-R6C1 2 2 a 2
7 myelin basic protein MBP H17696 69547 4155 18q23 brain--cerebellum;brain--hippocampus;infant brain;brain;multiple sclerosis lesions;brain--right hemisphere;brain--frontal lobe;melanocyte;fetal cochlea;T cells (activated);brain--cerebral cortex;muscle;embryo (8 week);fetal bone 50043 GRID- 1-R7C1 2 1 a 12
8 nerve growth factor, beta polypeptide NGFB T56316 2561 4803 1p13.1 fetal spleen;fetal brain 72869 P01138 Beta-nerve growth factor precursor (Beta-NGF). NERVE GROWTH FACTOR IS IMPORTANT FOR THE DEVELOPMENT AND MAINTENANCE OF THE SYMPATHETIC AND SENSORY NERVOUS SYSTEMS. IT STIMULATES DIVISION AND DIFFERENTIATION OF SYMPATHETIC AND EMBRYONIC SENSORY NEURONS. Growth factor, Signal 91222573 PF00243 Nerve growth factor family 4210 GRID- 1-R8C1 2 1 a 10
9 Opioid receptor, kappa1 R31938 134322 4210 GRID- 1-R9C1 2 1 a 8
10 protein kinase C, alpha PRKCA AA030029 169449 5578 17q22-q23.2 uterus (pregnant);B-Cell;retina;blood;infant brain;ovary 469954 P17252 Protein kinase C, alpha type (EC 2.7.1.-) (PKC-alpha). PKC IS ACTIVATED BY DIACYLGLYCEROL WHICH IN TURN PHOSPHORYLATES A RANGE OF CELLULAR PROTEINS. PKC ALSO SERVES AS THE RECEPTOR FOR PHORBOL ESTERS, A CLASS OF TUMOR PROMOTERS. ATP-binding, Calcium-binding, Phorbol-ester binding, Phosphorylation, Repeat, Serine/threonine-protein kinase, Transferase, Zinc 90245676 PF00069, PF00130, PF00168, PF00433 Protein kinase domain, Phorbol esters/diacylglycerol binding domain (C1 domain), C2 domain, Protein kinase C terminal domain 00500, 00562, 00600, 00760, 00860 GRID- 1-R10C1 2 1 a 6
11 Ric (Drosophila)-like, expressed in neurons RIN N53351 47626 6014 18q12.2 infant brain;fetal brain;multiple sclerosis lesions 283954 GRID- 1-R11C1 2 1 a 4
12 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide YWHAH N90630 349530 7533 22q12.3 fetal liver/spleen;fetal heart;fetal lung;gall bladder;uterus (pregnant);brain--cerebral cortex;thyroid;B-Cell;brain;uterus;neuroepithelium (NT2RAMI);HeLa (cell line);brain--cerebellum;heart;NT2 neuronal precursor;T-cell lymphoma;retina;placenta;infant brain;colon (carcinoma, cell line Caco-2);fibroblast;melanocyte;fetal brain;breast;pancreatic islets;colon 292996 Q04917 14-3-3 protein eta (Protein AS1). ACTIVATES TYROSINE AND TRYPTOPHAN HYDROXYLASES IN THE PRESENCE OF CA(2+)/CALMODULIN-DEPENDENT PROTEIN KINASE II, AND STRONGLY ACTIVATES PROTEIN KINASE C. IS PROBABLY A MULTIFUNCTIONAL REGULATOR OF THE CELL SIGNALING PROCESSES MEDIATED BY BOTH KINASES. Acetylation, Brain, Multigene family, Neurone, Phosphorylation 93294871 PF00244 14-3-3 protein GRID- 1-R12C1 2 1 a 2
13 Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) MJD AA702422 66521 4287 14q24.3-q32.2 testis;multiple sclerosis lesions;lung;colon;fetal heart;fetal liver/spleen;T cells (activated);liver;ovary 447568 P54252 Machado-Joseph disease protein 1. Polymorphism, Triplet repeat expansion 95179166 PF02099, PF02809 Josephin, Ubiquitin interaction motif GRID- 1-R1C2 2 2 c 12
14 monoamine oxidase A MAOA AA011096 183109 4128 Xp11.4-p11.3 placenta;fetal liver/spleen;uterus (pregnant);thyroid;adipose tissue;prostate (tumor);infant brain;prostate;fetal lung;parathyroid gland (tumor);small intestine;colon;fetal heart;retina;liver;embryo (9 week);brain--hippocampus 359661 00260, 00330, 00340, 00350, 00360, 00380 GRID- 1-R2C2 2 2 c 10
15 nerve growth factor receptor (TNFR superfamily, member 16) NGFR R55303 1827 4804 17q21-q22 fetal heart;infant brain;breast;melanoma;synovial membrane;heart 154790 4210 GRID- 1-R3C2 2 2 c 8
16 oligodendrocyte myelin glycoprotein OMG H24006 194772 4974 17q11.2 infant brain;multiple sclerosis lesions;neonatal spinal cord;pancreatic islets 51373 P23515 Attached to the membrane by a GPI-anchor. Oligodendrocyte-myelin glycoprotein precursor. CELL ADHESION MOLECULE CONTRIBUTING TO THE INTERACTIVE PROCESS REQUIRED FOR MYELINATION IN THE CENTRAL NERVOUS SYSTEM. Cell adhesion, Glycoprotein, GPI-anchor, Leucine-rich repeat, Myelin, Repeat, Signal 88198371 PF00560, PF01462 Leucine Rich Repeat, Leucine rich repeat N-terminal domain GRID- 1-R4C2 2 2 c 6
17 phenylethanolamine N-methyltransferase N63192 1892 5409 17q21-q22 uterus;multiple sclerosis lesions 289857 P11086 Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase)(Noradrenaline N-methyltransferase). CONVERTS NORADRENALINE TO ADRENALINE. Catecholamine biosynthesis, Methyltransferase, Transferase 88217959 PF01234 NNMT/PNMT/TEMT family 350 GRID- 1-R5C2 2 2 c 4
18 ESTs AA446316 191622 781233 350 GRID- 1-R6C2 2 2 c 2
19 serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1 PI12 AA115876 78589 5274 3q26.31 infant brain;multiple sclerosis lesions;pineal gland;lung (carcinoma) 564621 Q99574 Secreted. Neuroserpin precursor (Protease inhibitor 12). SERINE PROTEASE INHIBITOR THAT INHIBITS PLASMINOGEN ACTIVATORS AND PLASMIN BUT NOT THROMBIN. MAY BE INVOLVED IN THE FORMATION OR REORGANIZATION OF SYNAPTIC CONNECTIONS AS WELL AS FOR SYNAPTIC PLASTICITY IN THE ADULT NERVOUS SYSTEM. MAY PROTECT NEURONS FROM CELL DAMAGE BY TISSUE-TYPE PLASMINOGEN ACTIVATOR. Disease mutation, Glycoprotein, Serine protease inhibitor, Serpin, Signal 99445223 PF00079 Serpin (serine protease inhibitor) GRID- 1-R7C2 2 1 c 12
20 GDNF family receptor alpha 2 GFRA2 H12981 19317 2675 8p22-p21 infant brain;fetal liver/spleen;fetal heart 43207 O15328 Attached to the membrane by a GPI-anchor (By similarity). Neurturin receptor alpha precursor (NTNR-alpha) (NRTNR-alpha) (TGF-beta related neurotrophic factor receptor 2) (GDNF receptor beta)(GDNFR-beta) (RET ligand 2) (GFR-alpha 2). RECEPTOR FOR NEURTURIN. MEDIATES THE NRTN-INDUCED AUTOPHOSPHORYLATION AND ACTIVATION OF THE RET RECEPTOR. ALSO ABLE TO MEDIATE GDNF SIGNALING THROUGH THE RET TYROSINE KINASE RECEPTOR. Alternative splicing, Glycoprotein, GPI-anchor, Membrane, Receptor, Signal 97322356 GRID- 1-R8C2 2 1 c 10

Total number of rows: 1152

Table truncated, full table size 506 Kbytes.




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