GEO help: Mouse over screen elements for information.
Status
Public on Apr 21, 2008
Title
Eppendorf DualChip Human Cancer v1.1
Technology type
spotted DNA/cDNA
Distribution
custom-commercial
Organism
Homo sapiens
Manufacturer
Eppendorf AG, Hamburg, Germany
Manufacture protocol
Each slide features two identical microarrays, printed side-by-side. Unique Xmer® probe technology features 200-400 nucleotides long sense DNA. Each Xmer® is in silico designed and tested in real hybridization experiments.
Catalog number
0038 960 003
Support
glass
Description
No. of genes: 294 (including housekeeping genes) No. of housekeeping genes: 13 No. of spots per gene: 3 Average spot size: 200 µm Controls: RNA spiking mixture, housekeeping genes, positive/negative hybridization controls, positive/negative detection controls No. of spiking RNAs for normalization: 6
Web link
http://www.eppendorf.de/int/index.php?sitemap=2.1&pb=81160b06d6c190cb&action=products&contentid=1&catalognode=28839&page=15
Contributor(s)
Scaruffi P , Moretti S , Cremonesi C , Bonassi S , Tonini G
Citation(s)
16706734
Submission date
Apr 16, 2008
Last update date
Apr 21, 2008
Contact name
PAOLA SCARUFFI
E-mail(s)
paola.scaruffi@hsanmartino.it
Organization name
"San Martino" Hospital
Lab
Center of Physiopathology of Human Reproduction
Street address
LARGO R. BENZI, 10
City
Genova
State/province
GE
ZIP/Postal code
16132
Country
Italy
Samples (2)
GSM281935 , GSM282642
Series (1)
GSE11225
Array-comparative genomic hybridization by using DualChip® human cancer 1.1 arrays
Data table header descriptions
ID
Gene Name
Official name of the gene represented by the probe
GB_ACC
Entrez GenBank Accession Number
SP_ACC
Swissprot Accession Number
Aliases (HUGO)
A gene symbol, when one is available (from HUGO database)
Aliases (Entrez Gene)
A gene symbol, when one is available (from UniGene database)
General Function
Gene Ontology Consortium Molecular Function derived from LocusLink
Specific Function
Gene Ontology Consortium Specific Function derived from LocusLink
Row
Position in the array of the corresponding spot (row number in the array)
Col 1
Position in the array of the corresponding spot (column number in the array)
Col 2
Position in the array of the corresponding spot (column number in the array)
Col 3
Position in the array of the corresponding spot (column number in the array)
Data table
ID
Gene Name
GB_ACC
SP_ACC
Aliases (HUGO)
Aliases (Entrez Gene)
General Function
Specific Function
Row
Col 1
Col 2
Col 3
ADAM17
A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)
U69611.1
P78536
cSVP, CD156B, TACE
CD156b, MGC71942, TACE, cSVP
Notch signaling pathway / Epithelial cell signaling in Helicobacter pyloriinfection
Implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis
1
3
14
25
ADAM9
A disintegrin and metalloproteinase domain 9 (meltrin gamma)
NM_003816.1
Q13443
MDC9, KIAA0021, MCMP, Mltng
KIAA0021, MCMP, MDC9, Mltng
Protein kinase cascade
Implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis
1
4
15
26
ABI2
Abl-interactor 2
NM_005759.3
Q9NYB9
ABI-2, AIP-1, ABI2B, AblBP3, argBPIA, SSH3BP2
ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBPIA, argBPIB
Regulation of actin cytoskeleton
Cytoskeleton organization and biogenesis
1
5
16
27
ACVRL1
Activin A receptor type II-like 1
NM_000020.1
P37023
HHT2, ALK1, HHT, ACVRLK1, ORW2
ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3
TGF-beta signaling pathway
Type I cell-surface receptor for the TGF-beta superfamily
1
6
17
28
A2M
Alpha-2-macroglobulin
NM_000014.3
P01023
FWP007, S863-7, CPAMD5
CPAMD5, DKFZp779B086, FWP007, S863-7, alpha 2M
Complement and coagulation cascades / Alzheimer's disease
Protease inhibitor and cytokine transporter
1
7
18
29
AREG
Amphiregulin (schwannoma-derived growth factor)
NM_001657.1
P15514
SDGF
AR, CRDGF, MGC13647, SDGF
Cell proliferation
Growth factor activity
1
8
19
30
ANGPT1
Angiopoietin 1
U83508.1
Q15389
KIAA0003
AGP1, AGPT, ANG1
Cell differentiation
Roles in vascular development and angiogenesis
1
9
20
31
ATM
Ataxia telangiectasia mutated (includes complementation groups A, C and D)
U26455.1
Q13315
ATA, ATDC, ATC, ATD, TEL1
AT1, ATA, ATC, ATD, ATDC, ATE, DKFZp781A0353, MGC74674, TEL1
Cell cycle / Apoptosis / Toll-like receptor signaling pathway
Important cell cycle checkpoint kinase
1
10
21
32
ABCC1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
AJ003198.1
P33527
GS-X, MRP, MRP1
ABC29, ABCC, DKFZp781G125, GS-X, MRP, MRP1
ABC transporters - General
Multispecific organic anion transporter
1
11
22
33
AXL
AXL receptor tyrosine kinase
M76125.1
P30530
UFO
UFO
Signal transduction
Involved in the stimulation of cell proliferation
2
2
13
24
BIRC5
Baculoviral IAP repeat-containing 5 (survivin)
NM_001168.1
O15392
EPR-1, API4
API4, EPR-1
Apoptosis
Prevents apoptotic cell death
2
3
14
25
BSG
Basigin (OK blood group)
NM_001728.1
P35613
EMMPRIN, CD147, OK
5F7, CD147, EMMPRIN, M6, OK, TCSF
Extracellular matrix inducer
Involved in various immunologic phenomena, differentiation, and development
2
4
15
26
BCL2
B-cell CLL/lymphoma 2
NM_000633.1
P10415
Bcl-2
Bcl-2
Neurodegenerative Disorders / Apoptosis / Focal adhesion / Amyotrophic lateral sclerosis (ALS) / Prion disease
Blocks the apoptotic death of some cells such as lymphocytes
2
5
16
27
BAD
BCL2-antagonist of cell death
NM_004322.2
Q92934
BCL2L8, BBC2
BBC2, BCL2L8
Neurodegenerative Disorders / Apoptosis / Focal adhesion / Insulin signaling pathway / Amyotrophic lateral sclerosis (ALS)
Proapoptotic activity
2
7
18
29
BAK1
BCL2-antagonist/killer 1
U16811.1
Q16611
BCL2L7, CDN1
BAK, BCL2L7, CDN1, MGC117255
Apoptosis
Apoptotic mitochondrial changes
2
8
19
30
BAX
BCL2-associated X protein
NM_004324.1
Q8WXU1
/
Bax zeta
Neurodegenerative Disorders / Apoptosis / Amyotrophic lateral sclerosis (ALS)
Involved in a wide variety of cellular activities
2
9
20
31
BIK
BCL2-interacting killer (apoptosis-inducing)
NM_001197.3
Q13323
NBK, BBC1
BBC1, BIP1, BP4, NBK
Apoptosis
Target for antiapoptotic proteins
2
10
21
32
BCL2L2
BCL2-like 2
NM_004050.2
Q92843
KIAA0271, BCL-W
BCL-W, BCLW, KIAA0271
Apoptosis
Acts as anti- and pro-apoptotic regulators
3
1
12
23
BCL2A1
BCL2-related protein A1
NM_004049.2
Q16548
GRS, BFL1, BCL2L5, HBPA1
BCL2L5, BFL1, GRS, HBPA1
Apoptosis
Reduces the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation
3
2
13
24
BGN
Biglycan
NM_001711.3
P21810
DSPG1, SLRR1A
DSPG1, PG-S1, PGI, SLRR1A
Extracellular matrix
Function in connective tissue metabolism
3
4
15
26
Total number of rows: 293 Table truncated, full table size 64 Kbytes .
Supplementary data files not provided