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Platform GPL74 Query DataSets for GPL74
Status Public on Mar 11, 2002
Title [HC_G110] Affymetrix Human Cancer Array
Technology type in situ oligonucleotide
Distribution commercial
Organism Homo sapiens
Manufacturer Affymetrix
Manufacture protocol see manufacturer's web site
 
Description Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html

Has 2059 entries and was indexed 29-Jan-2002.
The Human Cancer G110 array enables focused and cost-effective expression studies in cancer biology. A panel of leading cancer researchers selected the specific set of 1,700 full-length human genes implicated in cancer that comprise this array. Accession numbers for sequences selected were selected from GenBank flat file release number 110.0.

Keywords = high density oligonucleotide array
 
Web link http://www.affymetrix.com/support/technical/byproduct.affx?product=hcg110
http://www.affymetrix.com/analysis/index.affx
Submission date Feb 19, 2002
Last update date Jun 03, 2009
Organization Affymetrix, Inc.
E-mail(s) geo@ncbi.nlm.nih.gov, support@affymetrix.com
Phone 888-362-2447
URL http://www.affymetrix.com/index.affx
Street address
City Santa Clara
State/province CA
ZIP/Postal code 95051
Country USA
 
Samples (23) GSM4312, GSM4313, GSM4314, GSM4315, GSM4316, GSM4317 
Series (1)
GSE468 Expression profiling of medulloblastoma

Data table header descriptions
ID Affymetrix Probe Set ID
GB_ACC GenBank Accession Number
SPOT_ID Sequence Type: Indicates whether the sequence is an Exemplar, Consensus or Control sequence. An Exemplar is a single nucleotide sequence taken directly from a public database. This sequence could be an mRNA or EST. A Consensus sequence, is a nucleotide sequence assembled by Affymetrix, based on one or more sequence taken from a public database.
Species Scientific Name The genus and species of the organism represented by the probe set.
Annotation Date The date that the annotations for this probe array were last updated. It will generally be earlier than the date when the annotations were posted on the Affymetrix web site.
Sequence Type
Sequence Source The database from which the sequence used to design this probe set was taken.
Target Description GenBank description associated with the representative public identifier. Blank for some probe sets.
Representative Public ID The accession number of a representative sequence. Note that for consensus-based probe sets, the representative sequence is only one of several sequences (sequence sub-clusters) used to build the consensus sequence and it is not directly used to derive the probe sequences. The representative sequence is chosen during array design as a sequence that is best associated with the transcribed region being interrogated by the probe set. Refer to the "Sequence Source" field to determine the database used.
Gene Title Title of Gene represented by the probe set.
Gene Symbol A gene symbol, when one is available (from UniGene).
ENTREZ_GENE_ID Entrez Gene Database UID
RefSeq Transcript ID References to multiple sequences in RefSeq. The field contains the ID and Description for each entry, and there can be multiple entries per ProbeSet.
Gene Ontology Biological Process Gene Ontology Consortium Biological Process derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Cellular Component Gene Ontology Consortium Cellular Component derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Molecular Function Gene Ontology Consortium Molecular Function derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".

Data table
ID GB_ACC SPOT_ID Species Scientific Name Annotation Date Sequence Type Sequence Source Target Description Representative Public ID Gene Title Gene Symbol ENTREZ_GENE_ID RefSeq Transcript ID Gene Ontology Biological Process Gene Ontology Cellular Component Gene Ontology Molecular Function
1000_at X60188 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human ERK1 mRNA for protein serine/threonine kinase X60188 mitogen-activated protein kinase 3 MAPK3 5595 NM_001040056 /// NM_001109891 /// NM_002746 0006468 // protein amino acid phosphorylation // inferred from direct assay /// 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // not recorded /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // not recorded /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation
1001_at X60957 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human tie mRNA for putative receptor tyrosine kinase X60957 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 TIE1 7075 NM_005424 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0045026 // plasma membrane fusion // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation
1002_f_at X65962 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Homo sapiens mRNA for cytochrome P-450 X65962 cytochrome P450, family 2, subfamily C, polypeptide 19 CYP2C19 1557 NM_000769 0055114 // oxidation reduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // traceable author statement /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0033767 // 4-hydroxyacetophenone monooxygenase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
1003_s_at X68149 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank HSBLR1A Homo sapiens BLR1 gene for Burkitt's lymphoma receptor 1 X68149 chemokine (C-X-C motif) receptor 5 CXCR5 643 NM_001716 /// NM_032966 0006928 // cell motion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation
1004_at X68149 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank HSBLR1A Homo sapiens BLR1 gene for Burkitt's lymphoma receptor 1 X68149 chemokine (C-X-C motif) receptor 5 CXCR5 643 NM_001716 /// NM_032966 0006928 // cell motion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // traceable author statement /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0042113 // B cell activation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation
1005_at X68277 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Homo sapiens CL 100 mRNA for protein tyrosine phosphatase X68277 dual specificity phosphatase 1 DUSP1 1843 NM_004417 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation
1006_at X07820 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human mRNA for metalloproteinase stromelysin-2 X07820 matrix metallopeptidase 10 (stromelysin 2) MMP10 4319 NM_002425 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0004222 // metalloendopeptidase activity // traceable author statement /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
1007_s_at U48705 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human receptor tyrosine kinase DDR gene; complete cds U48705 discoidin domain receptor tyrosine kinase 1 DDR1 780 NM_001954 /// NM_013993 /// NM_013994 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation
1008_f_at U50648 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human interferon-inducible RNA-dependent protein kinase (Pkr) gene U50648 eukaryotic translation initiation factor 2-alpha kinase 2 EIF2AK2 5610 NM_001135651 /// NM_001135652 /// NM_002759 0006412 // translation // inferred from electronic annotation /// 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006468 // protein amino acid phosphorylation // traceable author statement /// 0006926 // virus-infected cell apoptosis // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0046777 // protein amino acid autophosphorylation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation
1009_at U51004 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human putative protein kinase C inhibitor (PKCI-1) mRNA, complete cds U51004 histidine triad nucleotide binding protein 1 HINT1 3094 NM_005340 /// NR_024610 /// NR_024611 0007165 // signal transduction // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation
100_g_at Y08200 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Homo sapiens mRNA for rab geranylgeranyl transferase, alpha-subunit Y08200 Rab geranylgeranyltransferase, alpha subunit RABGGTA 5875 NM_004581 /// NM_182836 0006464 // protein modification process // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0018344 // protein geranylgeranylation // inferred from electronic annotation /// 0018346 // protein amino acid prenylation // inferred from electronic annotation 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004663 // Rab-protein geranylgeranyltransferase activity // traceable author statement /// 0004663 // Rab-protein geranylgeranyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008318 // protein prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
1010_at U53442 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human p38Beta MAP kinase mRNA; complete cds. U53442 mitogen-activated protein kinase 11 MAPK11 5600 NM_002751 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007243 // protein kinase cascade // inferred from direct assay /// 0007265 // Ras protein signal transduction // not recorded 0005654 // nucleoplasm // not recorded /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // not recorded /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008339 // MP kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation
1011_s_at U54778 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human 14-3-3 epsilon mRNA; complete cds U54778 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide YWHAE 7531 NM_006761 /// NR_024058 0001764 // neuron migration // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // traceable author statement /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0035308 // negative regulation of protein amino acid dephosphorylation // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation
1012_at U57317 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human p300/CBP-associated factor (P/CAF) mRNA, complete cds U57317 K(lysine) acetyltransferase 2B KAT2B 8850 NM_003884 0006338 // chromatin remodeling // non-traceable author statement /// 0006338 // chromatin remodeling // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006473 // protein amino acid acetylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded 0003712 // transcription cofactor activity // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction
1013_at U59913 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human chromosome 5 Mad homolog Smad5 mRNA; complete cds U59913 SMAD family member 5 SMAD5 4090 NM_001001419 /// NM_001001420 /// NM_005903 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007281 // germ cell development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // not recorded /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016021 // integral to membrane // non-traceable author statement 0003700 // transcription factor activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016563 // transcription activator activity // non-traceable author statement
1014_at U60325 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human DNA polymerase gamma mRNA, nuclear gene encoding mitochondrial protein, complete cds U60325 polymerase (DNA directed), gamma POLG 5428 NM_001126131 /// NM_002693 0006259 // DNA metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005760 // gamma DNA polymerase complex // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // traceable author statement /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation
1015_s_at U62293 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank LIMK1 gene (LIM-kinase1) extracted from Human LIM-kinase1 and alternatively spliced LIM-kinase1 (LIMK1) gene, complete cds U62293 LIM domain kinase 1 LIMK1 3984 NM_002314 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006468 // protein amino acid phosphorylation // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation
1016_s_at U70981 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human interleukin-13 receptor mRNA; complete cds U70981 interleukin 13 receptor, alpha 2 IL13RA2 3598 NM_000640 0005615 // extracellular space // traceable author statement /// 0005625 // soluble fraction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0004896 // cytokine receptor activity // traceable author statement /// 0004896 // cytokine receptor activity // inferred from electronic annotation
1017_at U73737 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human hMSH6 gene, 5' UTR and U73737 mutS homolog 6 (E. coli) MSH6 2956 NM_000179 0000710 // meiotic mismatch repair // inferred from sequence or structural similarity /// 0006281 // DNA repair // inferred from direct assay /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0008340 // determination of adult life span // inferred from electronic annotation /// 0008340 // determination of adult life span // inferred from sequence or structural similarity /// 0008629 // induction of apoptosis by intracellular signals // inferred from electronic annotation /// 0008629 // induction of apoptosis by intracellular signals // inferred from sequence or structural similarity /// 0008630 // DNA damage response, signal transduction resulting in induction of apoptosis // inferred from electronic annotation /// 0008630 // DNA damage response, signal transduction resulting in induction of apoptosis // inferred from sequence or structural similarity /// 0009411 // response to UV // inferred from electronic annotation /// 0009411 // response to UV // inferred from sequence or structural similarity /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from sequence or structural similarity /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from electronic annotation /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from sequence or structural similarity /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045190 // isotype switching // inferred from electronic annotation /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045910 // negative regulation of DNA recombination // inferred from electronic annotation /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0032301 // MutSalpha complex // inferred from direct assay /// 0032301 // MutSalpha complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0000701 // purine-specific mismatch base pair DNA N-glycosylase activity // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from electronic annotation /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032134 // mispaired DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from electronic annotation /// 0032139 // dinucleotide insertion or deletion binding // inferred from mutant phenotype /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032143 // single thymine insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043531 // ADP binding // inferred from direct assay
1018_at U81787 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank Human Wnt10B mRNA, complete cds. U81787 wingless-type MMTV integration site family, member 10B WNT10B 7480 NM_003394 0007165 // signal transduction // non-traceable author statement /// 0007223 // Wnt receptor signaling pathway, calcium modulating pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016055 // Wnt receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation

Total number of rows: 2059

Table truncated, full table size 3529 Kbytes.






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