|
| Status |
Public on Apr 11, 2018 |
| Title |
Differentially expressed miRNA in biological premature ovarian insufficiency (bPOI) |
| Platform organisms |
Homo sapiens; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Rhadinovirus; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Betapolyomavirus hominis; Betapolyomavirus macacae |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
We first examined changes of miRNAs and expression using microarrays ( Exiqon miRCURY™ microarray LNA v.18.0) of GCs from 10 bPOI and 10 age and BMI matched normal control women. Seventy-five miRNAs (Fold Change [FC]>2, P<0.05) were identified differentially expressed between bPOI patients and control women.
|
| |
|
| Overall design |
Our study is designed to demonstrate altered profiles of miRNAs in the granulosa cells from patients with bPOI. Functional studies will be further confirmed. This study will provide new viewpoint for understanding the roles of non-coding RNA for GCs function, as well as potential etiologic mechanism for POI.
|
| |
|
| Contributor(s) |
Dang Y |
| Citation(s) |
29367615 |
| |
| Submission date |
Jun 20, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Yujie Dang |
| E-mail(s) |
dangyujie@126.com
|
| Phone |
+8615098701901
|
| Organization name |
Center for Reproductive Medicine, Shandong University.
|
| Street address |
157 Jingliu Road
|
| City |
Jinan |
| ZIP/Postal code |
250021 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL19128 |
Exiqon miRCURY LNA microRNA array; 7th generation - hsa, mmu & rno (miRBase 18.0) |
|
| Samples (20)
|
|
| Relations |
| BioProject |
PRJNA391142 |
Less...
More...