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Series GSE100238 Query DataSets for GSE100238
Status Public on Apr 11, 2018
Title Differentially expressed miRNA in biological premature ovarian insufficiency (bPOI)
Platform organisms Homo sapiens; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Rhadinovirus; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Betapolyomavirus hominis; Betapolyomavirus macacae
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary We first examined changes of miRNAs and expression using microarrays ( Exiqon miRCURY™ microarray LNA v.18.0) of GCs from 10 bPOI and 10 age and BMI matched normal control women. Seventy-five miRNAs (Fold Change [FC]>2, P<0.05) were identified differentially expressed between bPOI patients and control women.
Overall design Our study is designed to demonstrate altered profiles of miRNAs in the granulosa cells from patients with bPOI. Functional studies will be further confirmed. This study will provide new viewpoint for understanding the roles of non-coding RNA for GCs function, as well as potential etiologic mechanism for POI.
Contributor(s) Dang Y
Citation(s) 29367615
Submission date Jun 20, 2017
Last update date Jul 25, 2021
Contact name Yujie Dang
Phone +8615098701901
Organization name Center for Reproductive Medicine, Shandong University.
Street address 157 Jingliu Road
City Jinan
ZIP/Postal code 250021
Country China
Platforms (1)
GPL19128 Exiqon miRCURY LNA microRNA array; 7th generation - hsa, mmu & rno (miRBase 18.0)
Samples (20)
GSM2676100 GC-92
GSM2676101 GC-94
GSM2676102 GC-95
BioProject PRJNA391142

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE100238_RAW.tar 19.0 Mb (http)(custom) TAR (of GPR)
GSE100238_normalized_data.txt.gz 104.9 Kb (ftp)(http) TXT
Processed data are available on Series record

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