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| Status |
Public on Jun 01, 2020 |
| Title |
Genome-wide expression of mRNAs and microRNAs in response to ERI2 knockdown |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
Here we describe the biological properties of new member of the Enhancer of RNAi (ERI) subfamily of DEDDh nucleases in humans, called ERI-2 that is important for miRNA processing and decay for a large subset of eukaryotic miRNA transcripts. hERI-2 is a potent Mg2+ dependent 3’-5’ exoribonuclease that also regulates the cell cycle and is a negative regulator of RISC.
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| |
|
| Overall design |
miRNA-seq and RNA-seq in ERI2 KD and control samples
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| |
|
| Contributor(s) |
Xi Y |
| Citation missing |
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| |
| Submission date |
Jun 28, 2017 |
| Last update date |
Jun 01, 2020 |
| Contact name |
Yuanxin Xi |
| E-mail(s) |
xiyuanxin@yahoo.com
|
| Phone |
530-220-2067
|
| Organization name |
The University of Texas MD Anderson Cancer Center
|
| Department |
Bioinformatics and Computational Biology
|
| Street address |
1400 Pressler St
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (12)
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| Relations |
| BioProject |
PRJNA392290 |
| SRA |
SRP110692 |
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