|
Status |
Public on Jun 01, 2020 |
Title |
Genome-wide expression of mRNAs and microRNAs in response to ERI2 knockdown |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing Non-coding RNA profiling by high throughput sequencing
|
Summary |
Here we describe the biological properties of new member of the Enhancer of RNAi (ERI) subfamily of DEDDh nucleases in humans, called ERI-2 that is important for miRNA processing and decay for a large subset of eukaryotic miRNA transcripts. hERI-2 is a potent Mg2+ dependent 3’-5’ exoribonuclease that also regulates the cell cycle and is a negative regulator of RISC.
|
|
|
Overall design |
miRNA-seq and RNA-seq in ERI2 KD and control samples
|
|
|
Contributor(s) |
Xi Y |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
|
Submission date |
Jun 28, 2017 |
Last update date |
Jun 01, 2020 |
Contact name |
Yuanxin Xi |
E-mail(s) |
xiyuanxin@yahoo.com
|
Phone |
530-220-2067
|
Organization name |
The University of Texas MD Anderson Cancer Center
|
Department |
Bioinformatics and Computational Biology
|
Street address |
1400 Pressler St
|
City |
Houston |
State/province |
TX |
ZIP/Postal code |
77030 |
Country |
USA |
|
|
Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
Samples (12)
|
|
Relations |
BioProject |
PRJNA392290 |
SRA |
SRP110692 |