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| Status |
Public on Jun 01, 2008 |
| Title |
Bioadhesive black rasberry gel effect on gene expression and proinflammatory proteins in human premalignant oral lesions |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
This portion of the study evaluated the effects of topical 10% black raspberry gel application on gene expression profiles of premalignant oral lesions. Topical application of the bioadhesive black rasberry gel was observed to modulate gene expression and reduce proinflammatory proteins in human premalignant oral lesions.
Keywords: Human oral tissues treated with 10% berry gfel
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| Overall design |
Each patient served as their own internal control. A pretreatment specimen of the premalignant lesion was obtained for baseline parameters. Following six weeks of treatment, the treated lesional tissue was removed. All tissue samples were immediately placed in RNA later and placed in a -80 degree freezer until sample preparation.
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| Contributor(s) |
Mallery SR, Zwick JC, Pei P, Tong M, Larsen PE, Shumway BS, Lu B, Fields HW, Mumper RJ, Stoner GD |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jan 14, 2008 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Ping Pei |
| E-mail(s) |
pei.4@osu.edu
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| Phone |
614-292-4028
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| Fax |
614-2920-9384
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| Organization name |
OSU
|
| Department |
Oral Pathology
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| Lab |
Dr. Mallery
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| Street address |
305 West 12th Ave
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| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43210 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (26)
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| Relations |
| BioProject |
PRJNA108381 |
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