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Status |
Public on Jul 30, 2017 |
Title |
Hierarchical Analysis of Multi-mapping RNA-Seq Reads Improves the Accuracy of Allele-specific Expression |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
RNA-seq experiment on reciprocal F1 hybrid cross between two diverse mouse strains NOD/ShiLtJ and PWK/PhJ to study the extent of Allele-specific expression (ASE) and the cause of ASE.
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Overall design |
Illumina 68bp single-end RNA-seq data from 48 reciprocal F1 mice. 24 male F1 progeny from each cross direction with two age and diet groups. In total, there are eight groups defined by three experimental factors cross-direction, diet and age with six biological replicates per group.
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Contributor(s) |
Raghupathy N, Choi K, Vincent MJ, Beane GL, Sheppard K, Munger SC, Korstanje R, Pardo-Manual de Villena F, Churchill GA |
Citation missing |
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Submission date |
Jul 24, 2017 |
Last update date |
May 15, 2019 |
Contact name |
Narayanan Raghupathy |
E-mail(s) |
narayanan.raghupathy@jax.org
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Phone |
2072886715
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Organization name |
The Jackson Laboratory
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Lab |
Churchill Lab
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Street address |
600 Main Street
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City |
Bar Harbor |
State/province |
ME |
ZIP/Postal code |
04609 |
Country |
USA |
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Platforms (1) |
GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
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Samples (96)
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Relations |
BioProject |
PRJNA395581 |
SRA |
SRP113491 |