|
| Status |
Public on Jan 04, 2018 |
| Title |
Angiogenic factor imbalance precedes complement deposition in the placenta of preeclamptic-like BPH/5 mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
BPH/5 mice are an inbred strain with “borderline hypertension” that spontaneously develops both maternal and fetal hallmarks of preeclampsia. RNA-Seq analysis of BPH/5 uterine implantation sites at embryonic day 7.5, the peak of decidualization, identifies differential expression of inflammatory response genes, including members of the complement family, compared to C57 controls.
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| |
|
| Overall design |
RNA-Seq was performed on RNA isolated from E7.5 BPH/5 and C57 implantation sites (n=4).
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| |
|
| Contributor(s) |
Sones JL, Grenier JK |
| Citation(s) |
29279353 |
| |
| Submission date |
Sep 10, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Jennifer K Grenier |
| Organization name |
Cornell University
|
| Department |
Biomedical Sciences
|
| Lab |
Biotechnology Building rm 333
|
| Street address |
526 Campus Rd
|
| City |
Ithaca |
| State/province |
NY |
| ZIP/Postal code |
14853 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (8)
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|
| Relations |
| BioProject |
PRJNA404000 |
| SRA |
SRP117214 |
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