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| Status |
Public on Feb 19, 2018 |
| Title |
Distinct, OR-specific subsets of axon guidance molecules govern early olfactory map formation |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We have discovered subsets of axon guidance molecules and transcription factors that are enriched in specific subsets of olfactory sensory neurons. We have demonstrated guidance activity for three of the candidate axon guidance genes we identified, suggesting that this approach is an efficient method for characterizing guidance systems relevant to olfactory axon targeting.
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| |
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| Overall design |
Single-cell RNASeq of OMP-expressing olfactory sensory neurons was performed by capture on Fluidigm-C1 followed by sequencing on Illumina HiSeq2500
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| Contributor(s) |
Dang P, Fisher SA, Stefanik D, Kim J, Raper J |
| Citation(s) |
29385124 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 DC012854 |
Targeting of sensory axons in the olfactory bulb |
UNIVERSITY OF PENNSYLVANIA |
JONATHAN A RAPER |
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| |
| Submission date |
Sep 11, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Junhyong Kim |
| Organization name |
University of Pennsylvania
|
| Department |
Biology
|
| Lab |
Junhyong Kim
|
| Street address |
433 S University Avenue
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL18413 |
Illumina HiSeq 2500 (Danio rerio) |
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| Samples (50)
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| Relations |
| BioProject |
PRJNA404067 |
| SRA |
SRP117248 |
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