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Series GSE10406 Query DataSets for GSE10406
Status Public on Feb 08, 2008
Title Mucus overproduction
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Our data demonstrates an increased number of submucosal glands in the sinus mucosa of pediatric patients with chronic rhinosinusitis (CRS). Additionally, data in the literature indicates differentially altered expression of innate markers of immunity and of inflammatory mediators in the sinus mucosa of adult patients with cystic fibrosis, non-CF controls, and controls.
Keywords: Differciation Study
 
Overall design Analyses will focus on inflammatory/immune response genes to identify genes in CRS or CF patients that are involved in pathways that impact on pathogenesis in these diseases. Analysis will also focus on genes in developmental pathways to identify mediators implicated in the development of submucosal glandular hyperplasia in pediatric patients with CRS.
 
Contributor(s) Rose M
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Submission date Feb 06, 2008
Last update date Oct 01, 2019
Contact name Eric P Hoffman
E-mail(s) ericphoffman@gmail.com
Organization name Binghamton University - SUNY
Department Pharmaceutical Sciences
Street address PO Box 6000
City Binghamton
State/province NY
ZIP/Postal code 13902
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (24)
GSM260377 Sinus mucosa tissue from the cystic fibrosis patient (SMOI-CF-1UP)
GSM260512 Sinus mucosa tissue from cystic fibrosis-patient with chronic rhinosinusitis (SMOI-CF-2UP)
GSM260513 Sinus mucosa tissue from cystic fibrosis-patient with chronic rhinosinusitis (SMOI-CF-4UP)
Relations
BioProject PRJNA108043

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE10406_RAW.tar 133.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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