|
| Status |
Public on Sep 24, 2018 |
| Title |
Changes in H3K27ac following LPS stimulation in pharyngeal epithelial cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report changes in H3K27ac following LPS stimulation in Detroit 562 cells. We were able to identified LPS-increased H3K27ac regions which correlated with RELA binding as well as gene up-regulation. This data set is relevant for airborne bacterial sensing as Detroit 562 cells are nasopharyngeal epithelial cells and LPS is a gram negative bacterial endotoxin.
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| |
|
| Overall design |
ChIP-seq for H3K27ac histone mark in Detroit 562 cells under no treatment control condition and after LPS stimulation, each condition in duplicates.
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| |
|
| Contributor(s) |
Borghini L |
| Citation(s) |
30587130, 31061469 |
| |
| Submission date |
Oct 05, 2017 |
| Last update date |
May 29, 2019 |
| Contact name |
Lisa Borghini |
| E-mail(s) |
borghinil99@gis.a-star.edu.sg
|
| Organization name |
GIS
|
| Department |
Infectious Diseases
|
| Lab |
Martin Hibberd
|
| Street address |
60 Biopolis Street, Genome, #02-01
|
| City |
Singapore |
| State/province |
Singapore |
| ZIP/Postal code |
138672 |
| Country |
Singapore |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA413376 |
| SRA |
SRP119459 |
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