|
| Status |
Public on Jan 01, 2018 |
| Title |
RNA-seq of Injured Nerve in Schwann cell conditional knockout of Eed |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal of the experiment was to determine the role of the polycomb repressive complex 2 in the nerve injury response in peripheral nerve. A Schwann cell specific knockout of the Eed subunit of PRC2 was generated to compare with wild type mice in sham and injured mice at 1d and 14d timepoints after nerve injury.
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| Overall design |
For each condition, three independent biological replicates were prepared (with the exception of the 14 d Eed ckO sample, which had only two replicates).
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| Contributor(s) |
Ma K, Svaren J |
| Citation(s) |
30306639 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 NS100510 |
Epigenetic Regulation of Nerve Injury |
UNIVERSITY OF WISCONSIN MADISON |
John P Svaren |
|
| |
| Submission date |
Nov 16, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
John Svaren |
| E-mail(s) |
jpsvaren@wisc.edu
|
| Organization name |
University of Wisconsin
|
| Department |
Comparative Biosciences
|
| Lab |
Waisman Center
|
| Street address |
1500 Highland Ave.
|
| City |
Madison |
| State/province |
WI |
| ZIP/Postal code |
53705 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (17)
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| This SubSeries is part of SuperSeries: |
| GSE106994 |
The role of Polycomb Repressive Complex 2 (PRC2) in Schwann cell responses to peripheral nerve injury |
|
| Relations |
| BioProject |
PRJNA418689 |
| SRA |
SRP125082 |
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