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Series GSE110086 Query DataSets for GSE110086
Status Public on Jun 14, 2018
Title Run or die in the evolution of de novo microRNAs
Organisms Drosophila erecta; Drosophila melanogaster; Drosophila sechellia; Drosophila simulans
Experiment type Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
Summary MicroRNAs (miRNAs) are a class of small, endogenous RNAs that regulate mRNA expressions post-transcriptionally. To study their expression, we collected and sequenced small RNA libraries in Drosophila species. To survey their regulation divergence, we dissected testes from miR-983 mutant and control flies in two sibling species and performed an RNA-seq analysis.
 
Overall design Two small RNA samples from D. erecta and D. sechellia testes as well as eight RNA-seq samples from D. melanogaster and D. simulans testes were analyzed. For RNA-seq, each genotype contains two biological replicates.
Web link https://www.biorxiv.org/content/early/2018/06/14/345769?rss=1
 
Contributor(s) Zhao Y, Yang H, Lin P, Liufu Z, Lu G, Xu J, Tang T, Wen H, Wu C
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Feb 02, 2018
Last update date Jan 23, 2019
Contact name Yixin Zhao
E-mail(s) yizhao@cshl.edu
Organization name Cold Spring Harbor Laboratory
Street address 1 Bungtown Road
City Cold Spring Harbor
State/province NEW YORK
ZIP/Postal code 11724
Country USA
 
Platforms (4)
GPL13304 Illumina HiSeq 2000 (Drosophila melanogaster)
GPL13306 Illumina HiSeq 2000 (Drosophila simulans)
GPL19321 Illumina HiSeq 2000 (Drosophila erecta)
Samples (10)
GSM2977392 D. melanogaster control replicate 1
GSM2977393 D. melanogaster control replicate 2
GSM2977394 D. melanogaster miR-983KO replicate 1
Relations
BioProject PRJNA432727
SRA SRP132078

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE110086_RAW.tar 8.1 Mb (http)(custom) TAR (of FA)
GSE110086_gene_expression.xlsx 1.1 Mb (ftp)(http) XLSX
GSE110086_miRNA_expression.xlsx 17.3 Kb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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