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Status |
Public on Feb 07, 2018 |
Title |
Murine epiSC control vs murine epiSC differentiated into dopaminergic neurons [mRNA] |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Transcriptional profiling of mouse embryonic, epiblast-derived, stem cells (epiSC). epiSC differentiated towards the dopaminergic phenotype were compared to control untreated epiSC. EpiSc were derived from a Pitx3-GFP mouse allowing visualization of dopaminergic (GFP+) differentiation efficiency.
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Overall design |
EpiSC derived from Pitx3-GFP mice were differentiated for fourteen days. Dopaminergic diffferentiation starts at day 5 with the addition of morphogens SHH and FGF8. Control cells were growth in absence of morphogens. Samples were collected in triplicate at day 5 (before the addition of SHH/FGF) and at day 9 and day 14 for both control and treated cells.
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Contributor(s) |
Costa V, Bellenchi GC, Li M, Greco D |
Citation(s) |
29526736 |
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Submission date |
Feb 06, 2018 |
Last update date |
May 09, 2018 |
Contact name |
Valerio Costa |
E-mail(s) |
valerio.costa@igb.cnr.it
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Phone |
+390816132617
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Organization name |
National Research Council
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Department |
Institute of Genetics and Biophysics
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Street address |
Via P. Castellino, 111
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City |
Naples |
State/province |
Italy |
ZIP/Postal code |
80131 |
Country |
Italy |
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Platforms (1) |
GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
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Samples (15)
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This SubSeries is part of SuperSeries: |
GSE110270 |
Murine epiSC control vs murine epiSC differentiated into dopaminergic neurons |
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Relations |
BioProject |
PRJNA433117 |