|
| Status |
Public on Feb 12, 2018 |
| Title |
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [ChIP-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
KMT2D plays a critical role in the control of epithelial enhancers and p63 target gene expression, including the re-quirement of KMT2D for the maintenance of epithelial progenitor gene expression and the coordination of proper terminal differentiation.
|
| |
|
| Overall design |
Characterization of KMT2D, p63 and several histone modifications' occupancy by ChIP-Seq in shRNA KO cell cultures.
|
| |
|
| Contributor(s) |
Lin-Shiao E, Capell BC |
| Citation(s) |
29440247 |
| |
| Submission date |
Feb 11, 2018 |
| Last update date |
Mar 26, 2019 |
| Contact name |
Yemin Lan |
| Organization name |
University of Pennsylvania
|
| Street address |
3400 Civic Center Blvd
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (15)
|
|
| This SubSeries is part of SuperSeries: |
| GSE110475 |
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis |
|
| Relations |
| BioProject |
PRJNA433767 |
| SRA |
SRP132655 |
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