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Series GSE110992 Query DataSets for GSE110992
Status Public on Feb 23, 2018
Title Microarray study of tumoral tissue transcriptome of breast cancer in mexican women who are overweight or obese
Organism Homo sapiens
Experiment type Expression profiling by array
Summary In this work, transcriptoma of invasive breast carcinoma was studied by means of microarray expression in Mexican women who are overweight or obese. The dysfunction of the adipokines signaling pathways has recently been linked to more aggressive features of breast cáncer. We hypothesized that there are changes related to the signaling of adipokines in the expression profile of invasive breast carcinoma of Mexican women with overweight or obesity. The objectives were as follows: 1) Determine the expression profile of tumour tissue of Mexican women who are overweight or obese by comparing tumoral tissue and non -tumoral tissue, both from the same patient, 2) Identification of over- or underexpressed genes involved in signalling pathways related to adipokines and the tumour process, 3) Identify the signalling pathways that presented genes with expression changes and were related to adipokines and the tumoural process.
 
Overall design Six independent pools: three samples from obese patients, two samples from obese patients, two samples from overweight patients, two samples from overweight patients, three samples from overweight patients, two samples from overweight patients, comprised of total RNA isolated from tumor and adjacent tissue.
 
Contributor(s) Floriano E, Ignacio I, Cardenas N, Brindis FG, Cordova MG, Comoto DA, Heredia AG, Millan A, Ortiz JL, Arroyo IM, Estrada LE
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Submission date Feb 22, 2018
Last update date Mar 27, 2018
Contact name Esau Floriano Sanchez
E-mail(s) floriano_esa@yahoo.com
Organization name SEDENA
Department Military School of Graduate of Health
Lab Multidisciplinary Research Laboratory
Street address Cerrada de Palomas SN
City Mexico City
ZIP/Postal code 11620
Country Mexico
 
Platforms (1)
GPL16699 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
Samples (6)
GSM3019802 CaM2_3: Tumor tissue vs adjacent tissue from obese women
GSM3019803 CaM1_3: Tumor tissue vs adjacent tissue from obese women
GSM3019804 CaM2_2: Tumor tissue vs adjacent tissue from overweight women
Relations
BioProject PRJNA435533

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE110992_RAW.tar 30.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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